HOX6_ORYSI
ID HOX6_ORYSI Reviewed; 249 AA.
AC Q9XH35; A2Z3C0; A5JPU3;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 2.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Homeobox-leucine zipper protein HOX6;
DE AltName: Full=HD-ZIP protein HOX6;
DE AltName: Full=Homeodomain transcription factor HOX6;
DE AltName: Full=OsHox6;
GN Name=HOX6; ORFNames=OsI_031063;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND TISSUE SPECIFICITY.
RC STRAIN=cv. IR58; TISSUE=Seed embryo;
RX PubMed=10732669; DOI=10.1007/pl00008671;
RA Meijer A.H., de Kam R.J., d'Erfurth I., Shen W.-B., Hoge J.H.C.;
RT "HD-Zip proteins of families I and II from rice: interactions and
RT functional properties.";
RL Mol. Gen. Genet. 263:12-21(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 135-249, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Minghui 86;
RX PubMed=17999151; DOI=10.1007/s11103-007-9255-7;
RA Agalou A., Purwantomo S., Oevernaes E., Johannesson H., Zhu X., Estiati A.,
RA de Kam R.J., Engstroem P., Slamet-Loedin I.H., Zhu Z., Wang M., Xiong L.,
RA Meijer A.H., Ouwerkerk P.B.F.;
RT "A genome-wide survey of HD-Zip genes in rice and analysis of drought-
RT responsive family members.";
RL Plant Mol. Biol. 66:87-103(2008).
CC -!- FUNCTION: Probable transcription factor that binds to the DNA sequence
CC 5'-CAAT[AT]ATTG-3'. {ECO:0000269|PubMed:10732669}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, leaves, nodes,
CC internodes, flowers and embryo. {ECO:0000269|PubMed:10732669,
CC ECO:0000269|PubMed:17999151}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD37699.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact leading to a deletion into the sequence.; Evidence={ECO:0000305};
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DR EMBL; AF145730; AAD37699.1; ALT_SEQ; mRNA.
DR EMBL; CM000134; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; EF555526; ABQ57269.1; -; mRNA.
DR AlphaFoldDB; Q9XH35; -.
DR SMR; Q9XH35; -.
DR STRING; 39946.Q9XH35; -.
DR Proteomes; UP000007015; Chromosome 9.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR045224; HDZip_class_I_plant.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR InterPro; IPR003106; Leu_zip_homeo.
DR PANTHER; PTHR24326; PTHR24326; 1.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..249
FT /note="Homeobox-leucine zipper protein HOX6"
FT /id="PRO_0000331684"
FT DNA_BIND 27..86
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..129
FT /note="Leucine-zipper"
FT REGION 194..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 27300 MW; 78DB44C421A4C708 CRC64;
MDGEEDSEWM MMDVGGKGGK GGGGGGAADR KKRFSEEQIK SLESMFATQT KLEPRQKLQL
ARELGLQPRQ VAIWFQNKRA RWKSKQLERE YSALRDDYDA LLCSYESLKK EKLALIKQLE
KLAEMLQEPR GKYGDNAGDD ARSGGVAGMK KEEFVGAGGA ATLYSSAEGG GTTTTTTAKL
MPHFGSDDVD AGLFLRPSSQ HHPPPPHAGA GFTSSEPAAD HQSFNFHSSW PSSTEQTCSS
TPWWEFESE
