HOX6_ORYSJ
ID HOX6_ORYSJ Reviewed; 249 AA.
AC Q651Z5; B7E407; Q0J065;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Homeobox-leucine zipper protein HOX6;
DE AltName: Full=HD-ZIP protein HOX6;
DE AltName: Full=Homeodomain transcription factor HOX6;
DE AltName: Full=OsHox6;
GN Name=HOX6; OrderedLocusNames=Os09g0528200, LOC_Os09g35910;
GN ORFNames=OJ1439_F07.36;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=10732669; DOI=10.1007/pl00008671;
RA Meijer A.H., de Kam R.J., d'Erfurth I., Shen W.-B., Hoge J.H.C.;
RT "HD-Zip proteins of families I and II from rice: interactions and
RT functional properties.";
RL Mol. Gen. Genet. 263:12-21(2000).
RN [6]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17999151; DOI=10.1007/s11103-007-9255-7;
RA Agalou A., Purwantomo S., Oevernaes E., Johannesson H., Zhu X., Estiati A.,
RA de Kam R.J., Engstroem P., Slamet-Loedin I.H., Zhu Z., Wang M., Xiong L.,
RA Meijer A.H., Ouwerkerk P.B.F.;
RT "A genome-wide survey of HD-Zip genes in rice and analysis of drought-
RT responsive family members.";
RL Plant Mol. Biol. 66:87-103(2008).
CC -!- FUNCTION: Probable transcription factor that binds to the DNA sequence
CC 5'-CAAT[AT]ATTG-3'. {ECO:0000269|PubMed:10732669}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, leaves, nodes,
CC internodes, flowers and embryo. {ECO:0000269|PubMed:10732669,
CC ECO:0000269|PubMed:17999151}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF25650.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP005681; BAD46372.1; -; Genomic_DNA.
DR EMBL; AP008215; BAF25650.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014965; BAT09072.1; -; Genomic_DNA.
DR EMBL; AK059755; BAG87104.1; -; mRNA.
DR EMBL; AK103160; BAG95926.1; -; mRNA.
DR RefSeq; XP_015612316.1; XM_015756830.1.
DR AlphaFoldDB; Q651Z5; -.
DR SMR; Q651Z5; -.
DR IntAct; Q651Z5; 1.
DR STRING; 4530.OS09T0528200-01; -.
DR PaxDb; Q651Z5; -.
DR PRIDE; Q651Z5; -.
DR EnsemblPlants; Os09t0528200-01; Os09t0528200-01; Os09g0528200.
DR EnsemblPlants; Os09t0528200-02; Os09t0528200-02; Os09g0528200.
DR GeneID; 4347647; -.
DR Gramene; Os09t0528200-01; Os09t0528200-01; Os09g0528200.
DR Gramene; Os09t0528200-02; Os09t0528200-02; Os09g0528200.
DR KEGG; osa:4347647; -.
DR eggNOG; KOG0483; Eukaryota.
DR HOGENOM; CLU_060842_3_1_1; -.
DR InParanoid; Q651Z5; -.
DR OMA; WWEFESL; -.
DR OrthoDB; 1130773at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR Genevisible; Q651Z5; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR045224; HDZip_class_I_plant.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR InterPro; IPR003106; Leu_zip_homeo.
DR PANTHER; PTHR24326; PTHR24326; 1.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..249
FT /note="Homeobox-leucine zipper protein HOX6"
FT /id="PRO_0000331685"
FT DNA_BIND 27..86
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..129
FT /note="Leucine-zipper"
FT REGION 194..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 27300 MW; 78DB44C421A4C708 CRC64;
MDGEEDSEWM MMDVGGKGGK GGGGGGAADR KKRFSEEQIK SLESMFATQT KLEPRQKLQL
ARELGLQPRQ VAIWFQNKRA RWKSKQLERE YSALRDDYDA LLCSYESLKK EKLALIKQLE
KLAEMLQEPR GKYGDNAGDD ARSGGVAGMK KEEFVGAGGA ATLYSSAEGG GTTTTTTAKL
MPHFGSDDVD AGLFLRPSSQ HHPPPPHAGA GFTSSEPAAD HQSFNFHSSW PSSTEQTCSS
TPWWEFESE
