ID   HOX71_XENLA             Reviewed;         295 AA.
AC   Q04281;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Homeobox protein XHOX-7.1;
DE   Flags: Fragment;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1679007; DOI=10.1242/dev.111.4.1179;
RA   Su M.-W., Suzuki H.R., Solursh M., Ramirez F.;
RT   "Progressively restricted expression of a new homeobox-containing gene
RT   during Xenopus laevis embryogenesis.";
RL   Development 111:1179-1187(1991).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Appears at the beginning of gastrulation. Plateau
CC       between the neurula and middle-tailbud stages, and decrease steadily
CC       thereafter.
CC   -!- SIMILARITY: Belongs to the Msh homeobox family. {ECO:0000305}.
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DR   EMBL; X58773; CAA41574.1; -; mRNA.
DR   PIR; A60131; A60131.
DR   AlphaFoldDB; Q04281; -.
DR   SMR; Q04281; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           <1..295
FT                   /note="Homeobox protein XHOX-7.1"
FT                   /id="PRO_0000049145"
FT   DNA_BIND        170..229
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          75..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          134..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..152
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
SQ   SEQUENCE   295 AA;  32338 MW;  054331E2BC106C10 CRC64;
     GDSLYGSHSP TVTSQLGSLC MAPALLMASY QPGVKIEERP LNRMQQTGVK PSLGEDKPKV
     PGILPFSVEA LMADRKPGRD RDLSSPTGSP LAGTSHSPRV GSIAAGETPN SPISLGNRYP
     VGAIMQLPEE TLLKPESPER SSWIQSPSFS PSPTRRMSPP ACPLRKHKTN RKPRTPFTTS
     QLLALERKFR QKQYLSIAER AEFSSSLNLT ETQVKIWFQN RRAKAKRLQE AELEKLKMAA
     KPMLPPAFGI SFPLGTPVPT ASLYGTSNPF QRQALPMSPM GLYTAHLGYS MYHLS