ID   HOX8_ORYSI              Reviewed;         281 AA.
AC   Q6V9S9;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Homeobox-leucine zipper protein HOX8;
DE   AltName: Full=HD-ZIP protein HOX8;
DE   AltName: Full=Homeodomain transcription factor HOX8;
DE   AltName: Full=OsHox8;
GN   Name=HOX8;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Yang L., Shen W.-B., Chen H., Jiang Y., Xu L.-L.;
RT   "Cloning of Oryza sativa homeodomain leucine-zipper protein (Hox8) gene and
RT   sequence analysis.";
RL   Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=17999151; DOI=10.1007/s11103-007-9255-7;
RA   Agalou A., Purwantomo S., Oevernaes E., Johannesson H., Zhu X., Estiati A.,
RA   de Kam R.J., Engstroem P., Slamet-Loedin I.H., Zhu Z., Wang M., Xiong L.,
RA   Meijer A.H., Ouwerkerk P.B.F.;
RT   "A genome-wide survey of HD-Zip genes in rice and analysis of drought-
RT   responsive family members.";
RL   Plant Mol. Biol. 66:87-103(2008).
CC   -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, stems, leaf blades
CC       and panicles. {ECO:0000269|PubMed:17999151}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AY346329; AAQ55492.1; -; mRNA.
DR   AlphaFoldDB; Q6V9S9; -.
DR   SMR; Q6V9S9; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR045224; HDZip_class_I_plant.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR003106; Leu_zip_homeo.
DR   PANTHER; PTHR24326; PTHR24326; 1.
DR   Pfam; PF02183; HALZ; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..281
FT                   /note="Homeobox-leucine zipper protein HOX8"
FT                   /id="PRO_0000331688"
FT   DNA_BIND        38..97
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          96..140
FT                   /note="Leucine-zipper"
FT   REGION          149..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..166
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   281 AA;  30046 MW;  2C406D6D471FAD42 CRC64;
     MRSYMDGGGA AAYEEEEEEV EDDDGGGGGG GGGGGGGLGE KKRRLAAEQV RALERSFEAD
     NKLDPERKAR IARDLRLHPR QVAVWFQNRR ARWKTKQIER DFAALRSRHD ALRLECDALR
     RDKDALAAEI ADLRDRVDGQ MSVKLEAVAA DEHQPPPPPP PPPLAYNSKV VDGSTDSDSS
     AVFNEEASPY SGAAIDHHHH QTPASYDTAG FTSFFAPSTT LTSSLSFPSM FHASSHFDGH
     QELLVGGGGA GAVADADLGG AGFFAGDEHA GGLSWYGAEG W