ID   HOXL_CUPNH              Reviewed;         107 AA.
AC   P31899; Q7WXU3;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 2.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Hydrogenase expression/formation protein HoxL;
GN   Name=hoxL; OrderedLocusNames=PHG006;
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OG   Plasmid megaplasmid pHG1.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1383192; DOI=10.1128/jb.174.19.6277-6289.1992;
RA   Kortlueke C., Horstmann K., Schwartz E., Rohde M., Binsack R.,
RA   Friedrich B.;
RT   "A gene complex coding for the membrane-bound hydrogenase of Alcaligenes
RT   eutrophus H16.";
RL   J. Bacteriol. 174:6277-6289(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=12948488; DOI=10.1016/s0022-2836(03)00894-5;
RA   Schwartz E., Henne A., Cramm R., Eitinger T., Friedrich B., Gottschalk G.;
RT   "Complete nucleotide sequence of pHG1: a Ralstonia eutropha H16 megaplasmid
RT   encoding key enzymes of H(2)-based lithoautotrophy and anaerobiosis.";
RL   J. Mol. Biol. 332:369-383(2003).
CC   -!- MISCELLANEOUS: Possibly a metalloprotein.
CC   -!- SIMILARITY: Belongs to the HupF/HypC family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M96433; AAA16466.1; -; Unassigned_DNA.
DR   EMBL; AY305378; AAP85762.1; -; Genomic_DNA.
DR   PIR; F43255; F43255.
DR   RefSeq; WP_011153931.1; NZ_CP039289.1.
DR   AlphaFoldDB; P31899; -.
DR   SMR; P31899; -.
DR   STRING; 381666.PHG006; -.
DR   EnsemblBacteria; AAP85762; AAP85762; PHG006.
DR   GeneID; 39976346; -.
DR   KEGG; reh:PHG006; -.
DR   PATRIC; fig|381666.6.peg.5; -.
DR   eggNOG; COG0298; Bacteria.
DR   HOGENOM; CLU_2104361_0_0_4; -.
DR   OMA; EPGHANC; -.
DR   OrthoDB; 2031925at2; -.
DR   Proteomes; UP000008210; Plasmid megaplasmid pHG1.
DR   InterPro; IPR019812; Hydgase_assmbl_chp_CS.
DR   InterPro; IPR001109; Hydrogenase_HupF/HypC.
DR   PANTHER; PTHR35177; PTHR35177; 1.
DR   Pfam; PF01455; HupF_HypC; 1.
DR   PRINTS; PR00445; HUPFHYPC.
DR   TIGRFAMs; TIGR00074; hypC_hupF; 1.
DR   PROSITE; PS01097; HUPF_HYPC; 1.
PE   3: Inferred from homology;
KW   Plasmid; Reference proteome.
FT   CHAIN           1..107
FT                   /note="Hydrogenase expression/formation protein HoxL"
FT                   /id="PRO_0000201387"
FT   CONFLICT        72..92
FT                   /note="LLGLDASEAQPRFELPSAMAR -> CWVLTHPKRNHVLNCHRRWP (in
FT                   Ref. 1; AAA16466)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   107 AA;  11641 MW;  A058858896333C1F CRC64;
     MCIGIPMQVM AIEPGYAVCA GRGERRRVSS ALVGDCQQGD WLLVFLDSAR ERIDALRAHE
     IDATLDMLQA ALLGLDASEA QPRFELPSAM AREDLAVLSN SRDSSSY