ID   1101L_ASFK5             Reviewed;         270 AA.
AC   P0C9G2;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 21.
DE   RecName: Full=Protein MGF 110-1L;
DE   Flags: Precursor;
GN   OrderedLocusNames=Ken-007;
OS   African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=561445;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:P18560}; Multi-
CC       pass membrane protein {ECO:0000250|UniProtKB:P18560}.
CC   -!- INDUCTION: Expressed in the immediate early phase of the viral
CC       replicative cycle. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 110 family. {ECO:0000305}.
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DR   EMBL; AY261360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000861; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR004848; ASFV_fam_110.
DR   Pfam; PF01639; v110; 2.
PE   3: Inferred from homology;
KW   Early protein; Glycoprotein; Membrane; Repeat; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000250|UniProtKB:A9JLI2"
FT   CHAIN           27..270
FT                   /note="Protein MGF 110-1L"
FT                   /id="PRO_0000373184"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1..146
FT                   /note="A"
FT   REPEAT          147..270
FT                   /note="B"
FT   CARBOHYD        75
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   270 AA;  32635 MW;  6A749F837813C6FA CRC64;
     MLGLQIITLL FIPTLLYAYE LEPLERTETP LEKELGYWCT YANHCSFCWD CQDGICRNKA
     FKNHSPILEN DYIANCSVYR RNDFCIYYIT SIKPHKIYRT ECSEHLSHEW HEAVIRKWQK
     LLTYGFYLVG CVLVVNYIRK RSLQTIVYLL VLLVIFFLLS QLMLYRELED KKHKTGSIPP
     ERELEHWCTH GKYCNFCWDC QNGICRNKVF KNHPPIGEND FIRYDCWTTH LLNKCYYEKI
     YKHFNTHIME CSQPTHFKWY DNLMKKQDIM