HPA1_PELLE
ID HPA1_PELLE Reviewed; 13 AA.
AC P32415;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Hemolytic protein A1;
DE Flags: Fragment;
OS Pelophylax lessonae (Pool frog) (Rana lessonae).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Pelophylax.
OX NCBI_TaxID=45623;
RN [1]
RP PROTEIN SEQUENCE, AND AMIDATION AT PHE-13.
RC TISSUE=Skin secretion;
RX PubMed=2317508; DOI=10.1016/0304-4165(90)90140-r;
RA Simmaco M., de Biase D., Severini C., Aita M., Erspamer G.F., Barra D.,
RA Bossa F.;
RT "Purification and characterization of bioactive peptides from skin extracts
RT of Rana esculenta.";
RL Biochim. Biophys. Acta 1033:318-323(1990).
CC -!- FUNCTION: Shows hemolytic activity.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed by the skin glands.
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DR PIR; S09018; S09018.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0044179; P:hemolysis in another organism; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Amphibian defense peptide; Cytolysis; Direct protein sequencing;
KW Hemolysis; Secreted.
FT CHAIN 1..>13
FT /note="Hemolytic protein A1"
FT /id="PRO_0000190092"
FT MOD_RES 13
FT /note="Phenylalanine amide"
FT /evidence="ECO:0000269|PubMed:2317508"
FT NON_TER 13
SQ SEQUENCE 13 AA; 1390 MW; C6BA768B9DFE587D CRC64;
FLPAIAGILS QLF
