ID   HPAA_HELPJ              Reviewed;         260 AA.
AC   Q9ZL47;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Neuraminyllactose-binding hemagglutinin;
DE   AltName: Full=Flagellar sheath adhesin;
DE   AltName: Full=N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit;
DE            Short=NLBH;
DE   Flags: Precursor;
GN   Name=hpaA; OrderedLocusNames=jhp_0733;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE001439; AAD06306.1; -; Genomic_DNA.
DR   PIR; C71896; C71896.
DR   RefSeq; WP_000855917.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZL47; -.
DR   SMR; Q9ZL47; -.
DR   STRING; 85963.jhp_0733; -.
DR   EnsemblBacteria; AAD06306; AAD06306; jhp_0733.
DR   KEGG; hpj:jhp_0733; -.
DR   PATRIC; fig|85963.30.peg.243; -.
DR   OMA; GCSPHII; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.160.180; -; 1.
DR   InterPro; IPR007876; NeuraminylLac-bd_hemagglutn.
DR   InterPro; IPR038531; NeuraminylLac-bd_hemagglutn_sf.
DR   Pfam; PF05211; NLBH; 1.
DR   PIRSF; PIRSF019714; Neuraminyllac-bd_haemagglutn; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           28..260
FT                   /note="Neuraminyllactose-binding hemagglutinin"
FT                   /id="PRO_0000018104"
FT   LIPID           28
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           28
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   260 AA;  29200 MW;  F5ED538C62B293B8 CRC64;
     MKTNGHFKDF AWKKCFLGAS VVALLVGCSP HIIETNEVAL KLNYHPASEK VQALDEKILL
     LRPAFQYSDN IAKEYENKFK NQTTLKVEEI LQNQGYKVIN VDSSDKDDFS FAQKKEGYLA
     VAMNGEIVLR PDPKRTIQKK SEPGLLFSTG LDKMEGVLIP AGFVKVTILE PMSGESLDSF
     TMDLSELDIQ EKFLKTTHSS HSGGLVSTMV KGTDNSNDAI KSALNKIFAS IMQEMDKKLT
     QRNLESYQKD AKELKNKRNR