ID   HPAA_HELPY              Reviewed;         260 AA.
AC   P55969;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Neuraminyllactose-binding hemagglutinin;
DE   AltName: Full=Flagellar sheath adhesin;
DE   AltName: Full=N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit;
DE            Short=NLBH;
DE   Flags: Precursor;
GN   Name=hpaA; OrderedLocusNames=HP_0797;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
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DR   EMBL; AE000511; AAD07844.1; -; Genomic_DNA.
DR   PIR; E64619; E64619.
DR   RefSeq; NP_207590.1; NC_000915.1.
DR   RefSeq; WP_000646667.1; NC_018939.1.
DR   AlphaFoldDB; P55969; -.
DR   SMR; P55969; -.
DR   DIP; DIP-3518N; -.
DR   IntAct; P55969; 7.
DR   MINT; P55969; -.
DR   STRING; 85962.C694_04085; -.
DR   PaxDb; P55969; -.
DR   EnsemblBacteria; AAD07844; AAD07844; HP_0797.
DR   KEGG; hpy:HP_0797; -.
DR   PATRIC; fig|85962.47.peg.849; -.
DR   OMA; GCSPHII; -.
DR   PhylomeDB; P55969; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.160.180; -; 1.
DR   InterPro; IPR007876; NeuraminylLac-bd_hemagglutn.
DR   InterPro; IPR038531; NeuraminylLac-bd_hemagglutn_sf.
DR   Pfam; PF05211; NLBH; 1.
DR   PIRSF; PIRSF019714; Neuraminyllac-bd_haemagglutn; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           28..260
FT                   /note="Neuraminyllactose-binding hemagglutinin"
FT                   /id="PRO_0000018100"
FT   LIPID           28
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           28
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   260 AA;  29040 MW;  D9F86C8B0556D071 CRC64;
     MKANNHFKDF AWKKCLLGAS VVALLVGCSP HIIETNEVAL KLNYHPASEK VQALDEKILL
     LRPAFQYSDN IAKEYENKFK NQTALKVEQI LQNQGYKVIS VDSSDKDDLS FSQKKEGYLA
     VAMNGEIVLR PDPKRTIQKK SEPGLLFSTG LDKMEGVLIP AGFVKVTILE PMSGESLDSF
     TMDLSELDIQ EKFLKTTHSS HSGGLVSTMV KGTDNSNDAI KSALNKIFAN IMQEIDKKLT
     QKNLESYQKD AKELKGKRNR