ID   HPAB1_PSESG             Reviewed;         523 AA.
AC   Q8RK12;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Effector protein hopAB1;
DE   AltName: Full=Protein virPphAPgy;
GN   Name=hopAB1; Synonyms=virPphAPgy;
OS   Pseudomonas savastanoi pv. glycinea (Pseudomonas syringae pv. glycinea).
OG   Plasmid pAOB1411.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=49a/90; PLASMID=pAOB1411;
RX   AGRICOLA=IND23295115; DOI=10.1046/j.1364-3703.2002.00121.x;
RA   Jackson R.W., Mansfield J.W., Ammouneh H., Dutton L.C., Wharton B.,
RA   Ortiz-Barredo A., Arnold D.L., Tsiamis G., Sesma A., Butcher D., Boch J.,
RA   Kim Y.J., Martin G.B., Tegli S., Murillo J., Vivian A.;
RT   "Location and activity of members of a family of virPphA homologues in
RT   pathovars of Pseudomonas syringae and P.savastanoi.";
RL   Mol. Plant Pathol. 3:205-216(2002).
CC   -!- FUNCTION: Effector protein that plays different roles depending on the
CC       species and plant cultivars that interact with the pathogen. Acts as a
CC       virulence determinant by enhancing the development of disease symptoms
CC       and bacterial growth. Acts as an avirulence factor by eliciting
CC       hypersensitive response (HR) and plant resistance. {ECO:0000269|Ref.1}.
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Secreted via type III secretion
CC       system (TTSS). {ECO:0000250}.
CC   -!- INDUCTION: Transcriptionally induced by HrpL. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the HopAB family. {ECO:0000305}.
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DR   EMBL; AJ439728; CAD29299.1; -; Genomic_DNA.
DR   RefSeq; WP_032704419.1; NZ_RBVH01000550.1.
DR   AlphaFoldDB; Q8RK12; -.
DR   SMR; Q8RK12; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   CDD; cd12803; HopAB_BID; 1.
DR   CDD; cd12802; HopAB_PID; 1.
DR   Gene3D; 1.20.1280.220; -; 1.
DR   Gene3D; 3.30.40.110; -; 1.
DR   InterPro; IPR015133; E3_ubiquit_lig_AvrPtoB.
DR   InterPro; IPR031759; HopAB_BAK-bd.
DR   InterPro; IPR038342; HopAB_BAK-bd_sf.
DR   InterPro; IPR038448; HopAB_E3_ubiquit_lig_sf.
DR   InterPro; IPR033743; HopAB_PID.
DR   Pfam; PF09046; AvrPtoB-E3_ubiq; 1.
DR   Pfam; PF16847; AvrPtoB_bdg; 1.
PE   3: Inferred from homology;
KW   Hypersensitive response elicitation; Plasmid; Secreted; Virulence.
FT   CHAIN           1..523
FT                   /note="Effector protein hopAB1"
FT                   /id="PRO_0000236791"
FT   REGION          1..94
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          165..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          299..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..67
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..214
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   523 AA;  57997 MW;  2F3264B6C4BA1374 CRC64;
     MPGINGAGPS NFFWQWRTDG EPVTEREHDS SRSASSANSP EFPPPASPAE SGRQRLLRSS
     ALSRQTREWL EATPARVQGA TPPAEARQSP EAQQAERIVQ ELVRGGADLN NVRTMLRNVM
     DNNAVAFSRV ERDILLQHFP NMLMTGISSD SVLANELRQR LRQTVRQQRI QSSTPARLAD
     SSSGSSQRSL IGRSTMLMTP GRSSSSSAAA SRTSVDRHPQ GLDLESNEVL RRLTQEGVDM
     ERLRTSLGRY IMSLEPLPPD LRRALESVGI NPFMPEDLSL VDHPVLNFSA ALNRMLASRQ
     TTTNSPELPP LASSAESGRR RLLRSPPLLS GQREWIEQNM RQEAEPQSSR LNRAVRLAVM
     PPQNENEDNV AYAIRLRRLN PGADVSRVVA SFITDPAARQ QVVNDIRAAL DIAPQFSQLR
     TISKADAESE ELGFRDAADH PDNATSCLFG EELSLSNPDQ QVIGLAVNPT DKPQPYSQEV
     NKALTFMDMK KLAQYLADKP EHPLNRQRLD AKNIAKYAFK IVP