ID   HPAB1_PSESS             Reviewed;         541 AA.
AC   Q8RK09;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Effector protein hopAB1;
DE   AltName: Full=Protein virPphAPsv;
GN   Name=hopAB1; Synonyms=virPphAPsv;
OS   Pseudomonas savastanoi (Pseudomonas syringae pv. savastanoi).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=29438;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=ITM317;
RX   AGRICOLA=IND23295115; DOI=10.1046/j.1364-3703.2002.00121.x;
RA   Jackson R.W., Mansfield J.W., Ammouneh H., Dutton L.C., Wharton B.,
RA   Ortiz-Barredo A., Arnold D.L., Tsiamis G., Sesma A., Butcher D., Boch J.,
RA   Kim Y.J., Martin G.B., Tegli S., Murillo J., Vivian A.;
RT   "Location and activity of members of a family of virPphA homologues in
RT   pathovars of Pseudomonas syringae and P.savastanoi.";
RL   Mol. Plant Pathol. 3:205-216(2002).
CC   -!- FUNCTION: Effector protein that plays different roles depending on the
CC       species and plant cultivars that interact with the pathogen. Acts as a
CC       virulence determinant by enhancing the development of disease symptoms
CC       and bacterial growth. Acts as an avirulence factor by eliciting
CC       hypersensitive response (HR) and plant resistance. {ECO:0000269|Ref.1}.
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Secreted via type III secretion
CC       system (TTSS). {ECO:0000250}.
CC   -!- INDUCTION: Transcriptionally induced by HrpL. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the HopAB family. {ECO:0000305}.
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DR   EMBL; AJ439729; CAD29302.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8RK09; -.
DR   BMRB; Q8RK09; -.
DR   SMR; Q8RK09; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   CDD; cd12803; HopAB_BID; 1.
DR   CDD; cd12802; HopAB_PID; 1.
DR   Gene3D; 1.20.1280.220; -; 1.
DR   Gene3D; 3.30.40.110; -; 1.
DR   InterPro; IPR015133; E3_ubiquit_lig_AvrPtoB.
DR   InterPro; IPR031759; HopAB_BAK-bd.
DR   InterPro; IPR038342; HopAB_BAK-bd_sf.
DR   InterPro; IPR038448; HopAB_E3_ubiquit_lig_sf.
DR   InterPro; IPR033743; HopAB_PID.
DR   Pfam; PF09046; AvrPtoB-E3_ubiq; 1.
DR   Pfam; PF16847; AvrPtoB_bdg; 1.
PE   3: Inferred from homology;
KW   Hypersensitive response elicitation; Secreted; Virulence.
FT   CHAIN           1..541
FT                   /note="Effector protein hopAB1"
FT                   /id="PRO_0000236792"
FT   REGION          1..94
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          168..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          317..338
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..67
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..216
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   541 AA;  59744 MW;  A35DA9EE1F2A1315 CRC64;
     MPGINGAGPS NFFWQWRTDG EPVTEREHDS SRSASSANSP ELPPPASPAE SGRQRLLRSS
     ALSRQTREWL EATPARVQGA NPPAEARQSP EAQQAERIVQ ELVRGGADLN NVRTMLRNVM
     DNNAVAFSRV ERDILLQHFP NMPMTGISSD SVLANELRQR LRQTVRQQRA LVQSSTPARL
     ADSSSGSSQR SLIGRSTMLM TPGRSSSSSA AASRTSVDRH PQGLDLESAR LASAARHNHS
     ANQTNEALRR LTQEGVDMER LRTSLGRYIM SLEPLPPDLR RALESVGINP FIPEELSLVD
     HPVLNFSAAL NRMLASRQTT TNSPELPPLA SSAESGRRRL LRSPPLLSGQ REWIEQNMRQ
     GAEPQSSRLN RAVRLAVMPP QKENEDNVAY AIRLRRLNPG ADVSRVVASF ITDPAARQQV
     VDDIRAALDI APQFSQLRTI SKADAESEEL GFRDAADHPD NATSCLFGEE LSLSNPDQQV
     IGLAVNPTDK PQPYSQEVNK ALTFMDMKKL AQYLADKPEH PLNRQRLDAK NISKYAFKIV
     P