ID   HPAB1_PSEU2             Reviewed;         516 AA.
AC   Q4ZMD6;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Effector protein hopAB1;
GN   Name=hopAB1; OrderedLocusNames=Psyr_4659;
OS   Pseudomonas syringae pv. syringae (strain B728a).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=205918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B728a;
RX   PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA   Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA   Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA   Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA   Kyrpides N.C., Ivanova N., Lindow S.E.;
RT   "Comparison of the complete genome sequences of Pseudomonas syringae pv.
RT   syringae B728a and pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC   -!- FUNCTION: Effector protein that plays different roles depending on the
CC       species and plant cultivars that interact with the pathogen. Acts as a
CC       virulence determinant by enhancing the development of disease symptoms
CC       and bacterial growth. Acts as an avirulence factor by eliciting
CC       hypersensitive response (HR) and plant resistance (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Secreted via type III secretion
CC       system (TTSS). {ECO:0000250}.
CC   -!- INDUCTION: Transcriptionally induced by HrpL. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the HopAB family. {ECO:0000305}.
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DR   EMBL; CP000075; AAY39686.1; -; Genomic_DNA.
DR   RefSeq; WP_011269154.1; NC_007005.1.
DR   RefSeq; YP_237724.1; NC_007005.1.
DR   AlphaFoldDB; Q4ZMD6; -.
DR   SMR; Q4ZMD6; -.
DR   STRING; 205918.Psyr_4659; -.
DR   PRIDE; Q4ZMD6; -.
DR   EnsemblBacteria; AAY39686; AAY39686; Psyr_4659.
DR   KEGG; psb:Psyr_4659; -.
DR   PATRIC; fig|205918.7.peg.4801; -.
DR   eggNOG; ENOG5030NBE; Bacteria.
DR   HOGENOM; CLU_505137_0_0_6; -.
DR   OMA; TSCLFGE; -.
DR   PHI-base; PHI:999; -.
DR   Proteomes; UP000000426; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   CDD; cd12803; HopAB_BID; 1.
DR   Gene3D; 1.20.1280.220; -; 1.
DR   Gene3D; 3.30.40.110; -; 1.
DR   InterPro; IPR015133; E3_ubiquit_lig_AvrPtoB.
DR   InterPro; IPR031759; HopAB_BAK-bd.
DR   InterPro; IPR038342; HopAB_BAK-bd_sf.
DR   InterPro; IPR038448; HopAB_E3_ubiquit_lig_sf.
DR   Pfam; PF09046; AvrPtoB-E3_ubiq; 1.
DR   Pfam; PF16847; AvrPtoB_bdg; 1.
PE   3: Inferred from homology;
KW   Hypersensitive response elicitation; Secreted; Virulence.
FT   CHAIN           1..516
FT                   /note="Effector protein hopAB1"
FT                   /id="PRO_0000236793"
FT   REGION          1..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          175..259
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..77
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..231
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        238..255
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   516 AA;  57607 MW;  5CECAC7405BE6A32 CRC64;
     MSGINGAGPS NFFWRWRADD EPVTERERDS SSGANLTNSP QLRPESPTVS GRRLLRSNAL
     SRQTREWQET TSASAERATP PVEPRQPPEA QPAERIVAER IVQELVRAGA NLNNVRTMLR
     NVMDNNAVAF SRVEWNILLQ HFPDMHTNGI SSDSVLANEL RQTLRQVVHQ QRTQRALAPI
     LSPAPSRPVA SSSRSSQRTL LGRFTGWMAP RQTSSSSQAT SSTSVDRHPQ DLNQLESLRL
     ADAERRNRSA NQTDTDEALR RLTQAGVDME RLSTSLGRYI HSFQPAPPDL RRLLESVGID
     PDIPEELTLV NNPVLNLNVA LNRMLASRQA TTESSSVFPS RAGDTRVRTL PVMPEREDNE
     NNVAYGVRLL RLNPEAEVER VVEAFITDPS SRPEVVADIH AVLRSITSQF RQLRTISKAD
     AESQDFRDAA DYPDDPTSCL FGEDLSLSNP HQQVIGLAGE STDILQPYSQ EGNKALRFMD
     MKKLAEHLAS KPVHPMNRDR LDDKNIAGYA FRVVPD