ID   HPB9_PELLE              Reviewed;          13 AA.
AC   P32416;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Hemolytic protein B9;
DE   Flags: Fragment;
OS   Pelophylax lessonae (Pool frog) (Rana lessonae).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Pelophylax.
OX   NCBI_TaxID=45623;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT PHE-13.
RC   TISSUE=Skin secretion;
RX   PubMed=2317508; DOI=10.1016/0304-4165(90)90140-r;
RA   Simmaco M., de Biase D., Severini C., Aita M., Erspamer G.F., Barra D.,
RA   Bossa F.;
RT   "Purification and characterization of bioactive peptides from skin extracts
RT   of Rana esculenta.";
RL   Biochim. Biophys. Acta 1033:318-323(1990).
CC   -!- FUNCTION: Shows hemolytic activity.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
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DR   PIR; S09019; S09019.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0044179; P:hemolysis in another organism; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Amphibian defense peptide; Cytolysis; Direct protein sequencing;
KW   Hemolysis; Secreted.
FT   CHAIN           1..>13
FT                   /note="Hemolytic protein B9"
FT                   /id="PRO_0000190093"
FT   MOD_RES         13
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|PubMed:2317508"
FT   NON_TER         13
SQ   SEQUENCE   13 AA;  1402 MW;  C6B41A765DF9287D CRC64;
     FLPLIAGLLG KLF