ID   HPF_ACIFI               Reviewed;          78 AA.
AC   P24694;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Ribosome hibernation promoting factor;
DE            Short=HPF;
DE   AltName: Full=Hibernation factor HPF;
DE   Flags: Fragment;
GN   Name=hpf;
OS   Acidithiobacillus ferridurans.
OC   Bacteria; Proteobacteria; Acidithiobacillia; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=1232575;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe;
RX   PubMed=2198257; DOI=10.1128/jb.172.8.4399-4406.1990;
RA   Berger D.K., Woods D.R., Rawlings D.E.;
RT   "Complementation of Escherichia coli sigma 54 (NtrA)-dependent formate
RT   hydrogenlyase activity by a cloned Thiobacillus ferrooxidans ntrA gene.";
RL   J. Bacteriol. 172:4399-4406(1990).
CC   -!- FUNCTION: Required for dimerization of active 70S ribosomes into 100S
CC       ribosomes in stationary phase; 100S ribosomes are translationally
CC       inactive and sometimes present during exponential growth.
CC       {ECO:0000250|UniProtKB:Q2FIN9}.
CC   -!- SUBUNIT: Associates exclusively with 100S ribosomes, which are dimers
CC       of 70S ribosomes. {ECO:0000250|UniProtKB:Q2FIN9}.
CC   -!- SIMILARITY: Belongs to the HPF/YfiA ribosome-associated protein family.
CC       Long HPF subfamily. {ECO:0000305}.
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DR   EMBL; M58480; AAA27380.1; -; Genomic_DNA.
DR   PIR; C37761; C37761.
DR   AlphaFoldDB; P24694; -.
DR   SMR; P24694; -.
DR   STRING; 380394.Lferr_2632; -.
DR   GO; GO:0044238; P:primary metabolic process; IEA:InterPro.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   CDD; cd00552; RaiA; 1.
DR   Gene3D; 3.30.160.100; -; 1.
DR   InterPro; IPR036567; RHF-like.
DR   InterPro; IPR003489; RHF/RaiA.
DR   Pfam; PF02482; Ribosomal_S30AE; 1.
DR   SUPFAM; SSF69754; SSF69754; 1.
DR   TIGRFAMs; TIGR00741; yfiA; 1.
PE   3: Inferred from homology;
KW   Translation regulation.
FT   CHAIN           1..>78
FT                   /note="Ribosome hibernation promoting factor"
FT                   /id="PRO_0000097427"
FT   NON_TER         78
SQ   SEQUENCE   78 AA;  8751 MW;  F39C7C4944E413EB CRC64;
     MQITITGQHL DLTDSIKNYA DEKIGRLGRY FDHVSNAQVV LKHLPHEKLS NVVDITVNAP
     GHVFHAEVHD ADMYTGID