ID   HPF_AZOVI               Reviewed;         107 AA.
AC   P17160; P05405;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Ribosome hibernation promoting factor;
DE            Short=HPF;
DE   AltName: Full=Hibernation factor HPF;
GN   Name=hpf;
OS   Azotobacter vinelandii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13705 / OP1 / DSM 366 / NCIMB 11614 / LMG 3878 / UW;
RX   PubMed=2695747; DOI=10.1111/j.1365-2958.1989.tb00162.x;
RA   Merrick M.J., Coppard J.R.;
RT   "Mutations in genes downstream of the rpoN gene (encoding sigma 54) of
RT   Klebsiella pneumoniae affect expression from sigma 54-dependent
RT   promoters.";
RL   Mol. Microbiol. 3:1765-1775(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-75.
RC   STRAIN=ATCC 13705 / OP1 / DSM 366 / NCIMB 11614 / LMG 3878 / UW;
RX   PubMed=3481423; DOI=10.1007/bf00325701;
RA   Merrick M.J., Gibbins J., Toukdarian A.;
RT   "The nucleotide sequence of the sigma factor gene ntrA (rpoN) of
RT   Azotobacter vinelandii: analysis of conserved sequences in NtrA proteins.";
RL   Mol. Gen. Genet. 210:323-330(1987).
CC   -!- FUNCTION: During stationary phase, promotes and stabilizes dimerization
CC       of 70S ribosomes by the ribosome modulation factor (RMF), leading to
CC       the formation of inactive 100S ribosomes.
CC       {ECO:0000250|UniProtKB:P0AFX0}.
CC   -!- SUBUNIT: Associates exclusively with 100S ribosomes, which are dimers
CC       of 70S ribosomes. {ECO:0000250|UniProtKB:P0AFX0}.
CC   -!- SIMILARITY: Belongs to the HPF/YfiA ribosome-associated protein family.
CC       Short HPF subfamily. {ECO:0000305}.
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DR   EMBL; X16334; CAA34389.1; -; Genomic_DNA.
DR   EMBL; X05888; CAA29315.1; -; Genomic_DNA.
DR   PIR; S07663; S07663.
DR   AlphaFoldDB; P17160; -.
DR   SMR; P17160; -.
DR   PRIDE; P17160; -.
DR   GO; GO:0044238; P:primary metabolic process; IEA:InterPro.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   CDD; cd00552; RaiA; 1.
DR   Gene3D; 3.30.160.100; -; 1.
DR   InterPro; IPR036567; RHF-like.
DR   InterPro; IPR003489; RHF/RaiA.
DR   Pfam; PF02482; Ribosomal_S30AE; 1.
DR   SUPFAM; SSF69754; SSF69754; 1.
DR   TIGRFAMs; TIGR00741; yfiA; 1.
PE   3: Inferred from homology;
KW   Translation regulation.
FT   CHAIN           1..107
FT                   /note="Ribosome hibernation promoting factor"
FT                   /id="PRO_0000097415"
SQ   SEQUENCE   107 AA;  12255 MW;  A4027E52FABC3160 CRC64;
     MQVNISGHQL DVTDALRDYV EEKISRLERH FDRITSVQVI MTVEKLKQKI EATLHVSGAE
     VVANAEHEDM YAAIDLLADK LDRQLIKHKE KQIERQQGQR PADSPVP