ID   HPF_PSEPK               Reviewed;         102 AA.
AC   P0A147; P15592;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Ribosome hibernation promoting factor;
DE            Short=HPF;
DE   AltName: Full=Hibernation factor HPF;
GN   Name=hpf; Synonyms=rpoX; OrderedLocusNames=PP_0951;
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2602128; DOI=10.1093/nar/17.23.10125;
RA   Koehler T., Cayrol J.M., Ramos J.L., Harayama S.;
RT   "Nucleotide and deduced amino acid sequence of the RpoN sigma-factor of
RT   Pseudomonas putida.";
RL   Nucleic Acids Res. 17:10125-10125(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440;
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F.,
RA   Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M., Hance I.,
RA   Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A.,
RA   Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H.,
RA   Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C.,
RA   Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
CC   -!- FUNCTION: During stationary phase, promotes and stabilizes dimerization
CC       of 70S ribosomes by the ribosome modulation factor (RMF), leading to
CC       the formation of inactive 100S ribosomes.
CC       {ECO:0000250|UniProtKB:P0AFX0}.
CC   -!- SUBUNIT: Associates exclusively with 100S ribosomes, which are dimers
CC       of 70S ribosomes. {ECO:0000250|UniProtKB:P0AFX0}.
CC   -!- SIMILARITY: Belongs to the HPF/YfiA ribosome-associated protein family.
CC       Short HPF subfamily. {ECO:0000305}.
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DR   EMBL; X16474; CAA34495.1; -; Genomic_DNA.
DR   EMBL; AE015451; AAN66576.1; -; Genomic_DNA.
DR   PIR; T01754; T01754.
DR   RefSeq; NP_743112.1; NC_002947.4.
DR   RefSeq; WP_003255135.1; NC_002947.4.
DR   AlphaFoldDB; P0A147; -.
DR   SMR; P0A147; -.
DR   STRING; 160488.PP_0951; -.
DR   EnsemblBacteria; AAN66576; AAN66576; PP_0951.
DR   GeneID; 58529347; -.
DR   GeneID; 61772631; -.
DR   GeneID; 64090762; -.
DR   GeneID; 66676506; -.
DR   KEGG; ppu:PP_0951; -.
DR   PATRIC; fig|160488.4.peg.1012; -.
DR   eggNOG; COG1544; Bacteria.
DR   HOGENOM; CLU_071472_3_1_6; -.
DR   OMA; NLTGHHI; -.
DR   PhylomeDB; P0A147; -.
DR   BioCyc; PPUT160488:G1G01-1025-MON; -.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0044238; P:primary metabolic process; IEA:InterPro.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   CDD; cd00552; RaiA; 1.
DR   Gene3D; 3.30.160.100; -; 1.
DR   InterPro; IPR036567; RHF-like.
DR   InterPro; IPR003489; RHF/RaiA.
DR   Pfam; PF02482; Ribosomal_S30AE; 1.
DR   SUPFAM; SSF69754; SSF69754; 1.
DR   TIGRFAMs; TIGR00741; yfiA; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Translation regulation.
FT   CHAIN           1..102
FT                   /note="Ribosome hibernation promoting factor"
FT                   /id="PRO_0000097422"
FT   CONFLICT        49
FT                   /note="K -> T (in Ref. 1; CAA34495)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   102 AA;  11501 MW;  564234177DE07673 CRC64;
     MQVNISGQHV EVTQPLRDYV LEKLARVESH FDKITNVQVI MKVEKLQQKV EATLQIPGGE
     VVANAEHEDM YAAIDALADK LDRQLKKHKE KQQSLLQGAA AR