HPF_PSEPU
ID HPF_PSEPU Reviewed; 102 AA.
AC P0A148; P15592;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 57.
DE RecName: Full=Ribosome hibernation promoting factor;
DE Short=HPF;
DE AltName: Full=Hibernation factor HPF;
GN Name=hpf; Synonyms=rpoX;
OS Pseudomonas putida (Arthrobacter siderocapsulatus).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=303;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=TN2100;
RX PubMed=2695395; DOI=10.1016/0378-1119(89)90474-5;
RA Inouye S., Yamada M., Nakazawa A., Nakazawa T.;
RT "Cloning and sequence analysis of the ntrA (rpoN) gene of Pseudomonas
RT putida.";
RL Gene 85:145-152(1989).
CC -!- FUNCTION: During stationary phase, promotes and stabilizes dimerization
CC of 70S ribosomes by the ribosome modulation factor (RMF), leading to
CC the formation of inactive 100S ribosomes.
CC {ECO:0000250|UniProtKB:P0AFX0}.
CC -!- SUBUNIT: Associates exclusively with 100S ribosomes, which are dimers
CC of 70S ribosomes. {ECO:0000250|UniProtKB:P0AFX0}.
CC -!- SIMILARITY: Belongs to the HPF/YfiA ribosome-associated protein family.
CC Short HPF subfamily. {ECO:0000305}.
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DR EMBL; M24916; AAA88445.1; -; Genomic_DNA.
DR PIR; JQ0339; JQ0339.
DR RefSeq; WP_003255135.1; NZ_VCPS01000007.1.
DR AlphaFoldDB; P0A148; -.
DR SMR; P0A148; -.
DR STRING; 1240350.AMZE01000051_gene864; -.
DR GeneID; 58529347; -.
DR GeneID; 61772631; -.
DR GeneID; 64090762; -.
DR GeneID; 66676506; -.
DR eggNOG; COG1544; Bacteria.
DR OMA; NLTGHHI; -.
DR OrthoDB; 2088581at2; -.
DR GO; GO:0044238; P:primary metabolic process; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR CDD; cd00552; RaiA; 1.
DR Gene3D; 3.30.160.100; -; 1.
DR InterPro; IPR036567; RHF-like.
DR InterPro; IPR003489; RHF/RaiA.
DR Pfam; PF02482; Ribosomal_S30AE; 1.
DR SUPFAM; SSF69754; SSF69754; 1.
DR TIGRFAMs; TIGR00741; yfiA; 1.
PE 3: Inferred from homology;
KW Translation regulation.
FT CHAIN 1..102
FT /note="Ribosome hibernation promoting factor"
FT /id="PRO_0000097423"
SQ SEQUENCE 102 AA; 11501 MW; 564234177DE07673 CRC64;
MQVNISGQHV EVTQPLRDYV LEKLARVESH FDKITNVQVI MKVEKLQQKV EATLQIPGGE
VVANAEHEDM YAAIDALADK LDRQLKKHKE KQQSLLQGAA AR