HPF_RHIME
ID HPF_RHIME Reviewed; 190 AA.
AC P17265;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=Ribosome hibernation promotion factor {ECO:0000255|HAMAP-Rule:MF_00839};
DE Short=HPF {ECO:0000255|HAMAP-Rule:MF_00839};
GN Name=hpf {ECO:0000255|HAMAP-Rule:MF_00839}; OrderedLocusNames=R00380;
GN ORFNames=SMc01140;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-105.
RX PubMed=3034856; DOI=10.1128/jb.169.6.2424-2431.1987;
RA Ronson C.W., Nixon B.T., Albright L.M., Ausubel F.M.;
RT "Rhizobium meliloti ntrA (rpoN) gene is required for diverse metabolic
RT functions.";
RL J. Bacteriol. 169:2424-2431(1987).
CC -!- FUNCTION: Required for dimerization of active 70S ribosomes into 100S
CC ribosomes in stationary phase; 100S ribosomes are translationally
CC inactive and sometimes present during exponential growth.
CC {ECO:0000255|HAMAP-Rule:MF_00839}.
CC -!- SUBUNIT: Interacts with 100S ribosomes. {ECO:0000255|HAMAP-
CC Rule:MF_00839}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00839}.
CC -!- SIMILARITY: Belongs to the HPF/YfiA ribosome-associated protein family.
CC Long HPF subfamily. {ECO:0000255|HAMAP-Rule:MF_00839}.
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DR EMBL; AL591688; CAC41817.1; -; Genomic_DNA.
DR EMBL; M16513; AAD15118.1; -; Genomic_DNA.
DR RefSeq; NP_384486.1; NC_003047.1.
DR RefSeq; WP_003527725.1; NC_003047.1.
DR AlphaFoldDB; P17265; -.
DR SMR; P17265; -.
DR STRING; 266834.SMc01140; -.
DR EnsemblBacteria; CAC41817; CAC41817; SMc01140.
DR GeneID; 61601859; -.
DR KEGG; sme:SMc01140; -.
DR PATRIC; fig|266834.11.peg.1752; -.
DR eggNOG; COG1544; Bacteria.
DR HOGENOM; CLU_071472_0_1_5; -.
DR OMA; RRLKDHH; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0044238; P:primary metabolic process; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR CDD; cd00552; RaiA; 1.
DR Gene3D; 3.30.160.100; -; 1.
DR Gene3D; 3.30.505.50; -; 1.
DR HAMAP; MF_00839; HPF; 1.
DR InterPro; IPR034694; HPF_long/plastid.
DR InterPro; IPR036567; RHF-like.
DR InterPro; IPR003489; RHF/RaiA.
DR InterPro; IPR032528; Ribosom_S30AE_C.
DR InterPro; IPR038416; Ribosom_S30AE_C_sf.
DR Pfam; PF16321; Ribosom_S30AE_C; 1.
DR Pfam; PF02482; Ribosomal_S30AE; 1.
DR SUPFAM; SSF69754; SSF69754; 1.
DR TIGRFAMs; TIGR00741; yfiA; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Translation regulation.
FT CHAIN 1..190
FT /note="Ribosome hibernation promotion factor"
FT /id="PRO_0000097425"
SQ SEQUENCE 190 AA; 21232 MW; C34BBF08D7B92CFE CRC64;
MSVRVSGKHM EIGDSFRVRI GEQIEQAVTK YFDGGYSSQV TVEKSGSRFS ADCKLHLDTG
VVLQANGQAN EPQSAFDAAS ERIEKRLRRY KRKLKDHHNG NGQNSTEVAY RVMDSVPFED
EEVPDDYAPT IVAETTKQLR TMSVANAVMA LDMTDEPVLM FRSPGKDDLN IVYRRNDGNI
GWIDAANIKA
