ID   HPF_SYNY3               Reviewed;         191 AA.
AC   P74518;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Ribosome hibernation promotion factor {ECO:0000255|HAMAP-Rule:MF_00839};
DE            Short=HPF {ECO:0000255|HAMAP-Rule:MF_00839};
DE   AltName: Full=Light-repressed protein A;
GN   Name=hpf {ECO:0000255|HAMAP-Rule:MF_00839}; Synonyms=lrtA;
GN   OrderedLocusNames=sll0947;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Required for dimerization of active 70S ribosomes into 100S
CC       ribosomes in stationary phase; 100S ribosomes are translationally
CC       inactive and sometimes present during exponential growth.
CC       {ECO:0000255|HAMAP-Rule:MF_00839}.
CC   -!- SUBUNIT: Interacts with 100S ribosomes. {ECO:0000255|HAMAP-
CC       Rule:MF_00839}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00839}.
CC   -!- SIMILARITY: Belongs to the HPF/YfiA ribosome-associated protein family.
CC       Long HPF subfamily. {ECO:0000255|HAMAP-Rule:MF_00839}.
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DR   EMBL; BA000022; BAA18622.1; -; Genomic_DNA.
DR   PIR; S76493; S76493.
DR   AlphaFoldDB; P74518; -.
DR   SMR; P74518; -.
DR   IntAct; P74518; 1.
DR   STRING; 1148.1653710; -.
DR   PaxDb; P74518; -.
DR   PRIDE; P74518; -.
DR   EnsemblBacteria; BAA18622; BAA18622; BAA18622.
DR   KEGG; syn:sll0947; -.
DR   eggNOG; COG1544; Bacteria.
DR   InParanoid; P74518; -.
DR   OMA; HGGYGVI; -.
DR   PhylomeDB; P74518; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IBA:GO_Central.
DR   GO; GO:0043022; F:ribosome binding; IBA:GO_Central.
DR   GO; GO:0045900; P:negative regulation of translational elongation; IBA:GO_Central.
DR   GO; GO:0044238; P:primary metabolic process; IEA:InterPro.
DR   CDD; cd00552; RaiA; 1.
DR   DisProt; DP02105; -.
DR   Gene3D; 3.30.160.100; -; 1.
DR   Gene3D; 3.30.505.50; -; 1.
DR   HAMAP; MF_00839; HPF; 1.
DR   InterPro; IPR034694; HPF_long/plastid.
DR   InterPro; IPR036567; RHF-like.
DR   InterPro; IPR003489; RHF/RaiA.
DR   InterPro; IPR032528; Ribosom_S30AE_C.
DR   InterPro; IPR038416; Ribosom_S30AE_C_sf.
DR   Pfam; PF16321; Ribosom_S30AE_C; 1.
DR   Pfam; PF02482; Ribosomal_S30AE; 1.
DR   SUPFAM; SSF69754; SSF69754; 1.
DR   TIGRFAMs; TIGR00741; yfiA; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Translation regulation.
FT   CHAIN           1..191
FT                   /note="Ribosome hibernation promotion factor"
FT                   /id="PRO_0000208588"
SQ   SEQUENCE   191 AA;  21895 MW;  400455FA62B26921 CRC64;
     MKLLIQGNNI TVTEAIHDYV EEKVERAVKH FQNLTTKVDV HLSVARNARI TNKHKAEVTV
     YANGTVIRAQ EGSENLYASI DLVADKIARQ LRKYKERIQD KQHGNVKTSE IVEDKPVEEN
     LIGDRAPELP SEVLRMKYFA MPPMAIEDAL EQLQLVDHDF YMFRNKDTDE INVIYIRNHG
     GYGVIQPHQA S