AP15A_XENLA
ID AP15A_XENLA Reviewed; 120 AA.
AC Q6IRQ9;
DT 16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 44.
DE RecName: Full=Anaphase-promoting complex subunit 15A;
GN Name=anapc15-a;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the anaphase promoting complex/cyclosome
CC (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls
CC progression through mitosis and the G1 phase of the cell cycle.
CC {ECO:0000250}.
CC -!- SUBUNIT: The APC/C is composed of at least 12 subunits. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the APC15 family. {ECO:0000305}.
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DR EMBL; BC070624; AAH70624.1; -; mRNA.
DR RefSeq; NP_001084966.1; NM_001091497.1.
DR AlphaFoldDB; Q6IRQ9; -.
DR SMR; Q6IRQ9; -.
DR DNASU; 432025; -.
DR GeneID; 432025; -.
DR KEGG; xla:432025; -.
DR CTD; 432025; -.
DR OMA; EGTDQDQ; -.
DR OrthoDB; 1586519at2759; -.
DR Proteomes; UP000186698; Chromosome 6S.
DR Bgee; 432025; Expressed in egg cell and 19 other tissues.
DR GO; GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0090266; P:regulation of mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.
DR InterPro; IPR026182; ANAPC15.
DR PANTHER; PTHR22526; PTHR22526; 1.
DR Pfam; PF15243; ANAPC15; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Mitosis; Reference proteome.
FT CHAIN 1..120
FT /note="Anaphase-promoting complex subunit 15A"
FT /id="PRO_0000417540"
FT REGION 47..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..112
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 120 AA; 13942 MW; D87ADD3AA23EFD22 CRC64;
MSTLFPSLFP QVTDSLWFNL DRPCVDENEL QQQEQQHQAW LLSIAEKDTG LVPIGKPASE
PYDEEEEEDD EDDEDSEEDS EDDEDMQDMD EMNDYNESPD DGEIEADMEG AEQDQDQWMI