ID   HPRL2_HALMA             Reviewed;         189 AA.
AC   Q5UX13;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=HGPRTase-like protein 2 {ECO:0000255|HAMAP-Rule:MF_01467};
DE            EC=2.4.2.- {ECO:0000255|HAMAP-Rule:MF_01467};
GN   OrderedLocusNames=rrnAC3523;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- FUNCTION: May catalyze a purine salvage reaction, the substrate is
CC       unknown. {ECO:0000255|HAMAP-Rule:MF_01467}.
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family. Archaeal HPRT subfamily. {ECO:0000255|HAMAP-Rule:MF_01467}.
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DR   EMBL; AY596297; AAV48190.1; -; Genomic_DNA.
DR   RefSeq; WP_004518711.1; NZ_CP039138.1.
DR   AlphaFoldDB; Q5UX13; -.
DR   SMR; Q5UX13; -.
DR   STRING; 272569.rrnAC3523; -.
DR   EnsemblBacteria; AAV48190; AAV48190; rrnAC3523.
DR   GeneID; 40154293; -.
DR   KEGG; hma:rrnAC3523; -.
DR   PATRIC; fig|272569.17.peg.4027; -.
DR   eggNOG; arCOG00030; Archaea.
DR   HOGENOM; CLU_126376_0_0_2; -.
DR   OMA; FIHPISD; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   HAMAP; MF_01467; Hypx_phosphoribosyltr; 1.
DR   InterPro; IPR026597; HGPRTase-like.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   SUPFAM; SSF53271; SSF53271; 1.
DR   PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1.
PE   3: Inferred from homology;
KW   Purine salvage; Reference proteome; Transferase.
FT   CHAIN           1..189
FT                   /note="HGPRTase-like protein 2"
FT                   /id="PRO_0000149494"
SQ   SEQUENCE   189 AA;  20638 MW;  71F9B5DA71FCAE24 CRC64;
     MDRLKKSLLE APIIEKEGYH YFVHPISDGV PMLRPELLRE IVIKIIRKAE LDDVDKIVTP
     AAMGIHISTA VSLMTDIPLV VVRKRQYGLD GEVSLSQVTG YSESEMYVND VYEGDQVLVL
     DDVLSTGGTL AGLTGALEDI GADIRDIVCV IKKADGTNKL DEAGYDAKTL INVQVIDGEV
     TIVDEHGDD