ID   HPRL2_HALVD             Reviewed;         181 AA.
AC   D4GVW6;
DT   22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=HGPRTase-like protein 2 {ECO:0000255|HAMAP-Rule:MF_01467};
DE            EC=2.4.2.- {ECO:0000255|HAMAP-Rule:MF_01467};
GN   OrderedLocusNames=HVO_2250;
OS   Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS   NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloferax.
OX   NCBI_TaxID=309800;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC   B-1768 / DS2;
RX   PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA   Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA   Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA   Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT   "The complete genome sequence of Haloferax volcanii DS2, a model
RT   archaeon.";
RL   PLoS ONE 5:E9605-E9605(2010).
CC   -!- FUNCTION: May catalyze a purine salvage reaction, the substrate is
CC       unknown. {ECO:0000255|HAMAP-Rule:MF_01467}.
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family. Archaeal HPRT subfamily. {ECO:0000255|HAMAP-Rule:MF_01467}.
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DR   EMBL; CP001956; ADE04456.1; -; Genomic_DNA.
DR   RefSeq; WP_004042138.1; NZ_AOHU01000041.1.
DR   AlphaFoldDB; D4GVW6; -.
DR   SMR; D4GVW6; -.
DR   STRING; 309800.C498_06523; -.
DR   EnsemblBacteria; ADE04456; ADE04456; HVO_2250.
DR   GeneID; 8925144; -.
DR   KEGG; hvo:HVO_2250; -.
DR   eggNOG; arCOG00030; Archaea.
DR   HOGENOM; CLU_126376_0_0_2; -.
DR   OMA; EMFINDI; -.
DR   OrthoDB; 88302at2157; -.
DR   Proteomes; UP000008243; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   HAMAP; MF_01467; Hypx_phosphoribosyltr; 1.
DR   InterPro; IPR026597; HGPRTase-like.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   SUPFAM; SSF53271; SSF53271; 1.
DR   PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1.
PE   3: Inferred from homology;
KW   Purine salvage; Reference proteome; Transferase.
FT   CHAIN           1..181
FT                   /note="HGPRTase-like protein 2"
FT                   /id="PRO_0000415452"
SQ   SEQUENCE   181 AA;  19482 MW;  B0EC849C3EE4758E CRC64;
     MQRLEESLHE APIIDKDGYS YLVHPISNGV PMLDPQLLRE VVVGITRAAD LDVDKIVAPE
     AMGIHIATAL SLQTDVPLVV IRKREYGLDG EVALHQTTGY SESEMFINDI EDGDRVLVVD
     DLLSTGGTLA AICGALDDIG AEVSDIVVAI RKVGETALDD TDYEATSLVD ISVDEDGVEI
     H