ID   HPRL2_HALWD             Reviewed;         181 AA.
AC   Q18IJ5;
DT   22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=HGPRTase-like protein 2 {ECO:0000255|HAMAP-Rule:MF_01467};
DE            EC=2.4.2.- {ECO:0000255|HAMAP-Rule:MF_01467};
GN   OrderedLocusNames=HQ_2050A;
OS   Haloquadratum walsbyi (strain DSM 16790 / HBSQ001).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloquadratum.
OX   NCBI_TaxID=362976;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16790 / HBSQ001;
RX   PubMed=16820047; DOI=10.1186/1471-2164-7-169;
RA   Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F.,
RA   Pfeiffer F., Oesterhelt D.;
RT   "The genome of the square archaeon Haloquadratum walsbyi: life at the
RT   limits of water activity.";
RL   BMC Genomics 7:169-169(2006).
CC   -!- FUNCTION: May catalyze a purine salvage reaction, the substrate is
CC       unknown. {ECO:0000255|HAMAP-Rule:MF_01467}.
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family. Archaeal HPRT subfamily. {ECO:0000255|HAMAP-Rule:MF_01467}.
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DR   EMBL; AM180088; CAJ52177.1; -; Genomic_DNA.
DR   RefSeq; WP_011571316.1; NC_008212.1.
DR   AlphaFoldDB; Q18IJ5; -.
DR   SMR; Q18IJ5; -.
DR   STRING; 362976.HQ_2050A; -.
DR   EnsemblBacteria; CAJ52177; CAJ52177; HQ_2050A.
DR   GeneID; 4193705; -.
DR   KEGG; hwa:HQ_2050A; -.
DR   eggNOG; arCOG00030; Archaea.
DR   HOGENOM; CLU_126376_0_0_2; -.
DR   OMA; EMFINDI; -.
DR   Proteomes; UP000001975; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   HAMAP; MF_01467; Hypx_phosphoribosyltr; 1.
DR   InterPro; IPR026597; HGPRTase-like.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   SUPFAM; SSF53271; SSF53271; 1.
DR   PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1.
PE   3: Inferred from homology;
KW   Purine salvage; Reference proteome; Transferase.
FT   CHAIN           1..181
FT                   /note="HGPRTase-like protein 2"
FT                   /id="PRO_0000415455"
SQ   SEQUENCE   181 AA;  19698 MW;  3DAE2C4788957997 CRC64;
     MERLHESLHE APIIDKDGYE YLVHPISNGV PVLEPGLLRE VVIDIMQQSD FNVDKIVAPE
     AMGIHLATAL SLQTDVPLVV IRKRSYGLPG EVALHKSTGY SESEMYINDI EAGDRILIID
     DLLSTGGTLA AICGALDDIG TEIIDIVVVI RKIGQSAMDE LEHDVTSLVD ITVEDGEVTI
     Q