HPRL_HALS3
ID HPRL_HALS3 Reviewed; 188 AA.
AC B0R3M8;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 70.
DE RecName: Full=HGPRTase-like protein {ECO:0000255|HAMAP-Rule:MF_01467};
DE EC=2.4.2.- {ECO:0000255|HAMAP-Rule:MF_01467};
GN OrderedLocusNames=OE_1840R;
OS Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=478009;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29341 / DSM 671 / R1;
RX PubMed=18313895; DOI=10.1016/j.ygeno.2008.01.001;
RA Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT R1 compared to that of strain NRC-1.";
RL Genomics 91:335-346(2008).
CC -!- FUNCTION: May catalyze a purine salvage reaction, the substrate is
CC unknown. {ECO:0000255|HAMAP-Rule:MF_01467}.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. Archaeal HPRT subfamily. {ECO:0000255|HAMAP-Rule:MF_01467}.
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DR EMBL; AM774415; CAP13342.1; -; Genomic_DNA.
DR RefSeq; WP_010902373.1; NC_010364.1.
DR AlphaFoldDB; B0R3M8; -.
DR SMR; B0R3M8; -.
DR EnsemblBacteria; CAP13342; CAP13342; OE_1840R.
DR GeneID; 5952595; -.
DR GeneID; 62886196; -.
DR KEGG; hsl:OE_1840R; -.
DR HOGENOM; CLU_126376_0_0_2; -.
DR OMA; FIHPISD; -.
DR PhylomeDB; B0R3M8; -.
DR Proteomes; UP000001321; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR HAMAP; MF_01467; Hypx_phosphoribosyltr; 1.
DR InterPro; IPR026597; HGPRTase-like.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR Pfam; PF00156; Pribosyltran; 1.
DR SUPFAM; SSF53271; SSF53271; 1.
DR PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1.
PE 3: Inferred from homology;
KW Purine salvage; Transferase.
FT CHAIN 1..188
FT /note="HGPRTase-like protein"
FT /id="PRO_1000088977"
SQ SEQUENCE 188 AA; 20613 MW; 22FC65E6D3E873D7 CRC64;
MDRLKQSLLD APIIEKDGYH YFVHPISDGV PMLEPELLRE IVIRIIRKAE LDEVDKIVTP
AAMGIHISTA VSLMTDIPIV VIRKREYGLP GEVALSQETG YSENEMYIND VHEGDRVLVL
DDVLSTGGTL RAITDALEQT GADVADVLAV IKKAGPNELD DTDMDVRTLI NVDVADGEVV
VVDDQGDH