HPRL_HALSA
ID HPRL_HALSA Reviewed; 188 AA.
AC Q9HRT1;
DT 30-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=HGPRTase-like protein {ECO:0000255|HAMAP-Rule:MF_01467};
DE EC=2.4.2.- {ECO:0000255|HAMAP-Rule:MF_01467};
GN OrderedLocusNames=VNG_0559G;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: May catalyze a purine salvage reaction, the substrate is
CC unknown. {ECO:0000255|HAMAP-Rule:MF_01467}.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. Archaeal HPRT subfamily. {ECO:0000255|HAMAP-Rule:MF_01467}.
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DR EMBL; AE004437; AAG19077.1; -; Genomic_DNA.
DR PIR; A84214; A84214.
DR RefSeq; WP_010902373.1; NC_002607.1.
DR AlphaFoldDB; Q9HRT1; -.
DR SMR; Q9HRT1; -.
DR STRING; 64091.VNG_0559G; -.
DR PaxDb; Q9HRT1; -.
DR DNASU; 1447382; -.
DR EnsemblBacteria; AAG19077; AAG19077; VNG_0559G.
DR GeneID; 5952595; -.
DR GeneID; 62886196; -.
DR KEGG; hal:VNG_0559G; -.
DR PATRIC; fig|64091.14.peg.425; -.
DR HOGENOM; CLU_126376_0_0_2; -.
DR InParanoid; Q9HRT1; -.
DR OMA; FIHPISD; -.
DR OrthoDB; 88302at2157; -.
DR PhylomeDB; Q9HRT1; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR HAMAP; MF_01467; Hypx_phosphoribosyltr; 1.
DR InterPro; IPR026597; HGPRTase-like.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR Pfam; PF00156; Pribosyltran; 1.
DR SUPFAM; SSF53271; SSF53271; 1.
DR PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1.
PE 3: Inferred from homology;
KW Purine salvage; Reference proteome; Transferase.
FT CHAIN 1..188
FT /note="HGPRTase-like protein"
FT /id="PRO_0000149495"
SQ SEQUENCE 188 AA; 20613 MW; 22FC65E6D3E873D7 CRC64;
MDRLKQSLLD APIIEKDGYH YFVHPISDGV PMLEPELLRE IVIRIIRKAE LDEVDKIVTP
AAMGIHISTA VSLMTDIPIV VIRKREYGLP GEVALSQETG YSENEMYIND VHEGDRVLVL
DDVLSTGGTL RAITDALEQT GADVADVLAV IKKAGPNELD DTDMDVRTLI NVDVADGEVV
VVDDQGDH