ID   HPR_BACC3               Reviewed;         185 AA.
AC   C1EKG1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=HTH-type transcriptional regulator Hpr {ECO:0000255|HAMAP-Rule:MF_01911};
DE   AltName: Full=Protease production regulatory protein Hpr {ECO:0000255|HAMAP-Rule:MF_01911};
GN   Name=hpr {ECO:0000255|HAMAP-Rule:MF_01911}; OrderedLocusNames=BCA_1081;
OS   Bacillus cereus (strain 03BB102).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=572264;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03BB102;
RA   Dodson R.J., Jackson P., Munk A.C., Brettin T., Bruce D., Detter C.,
RA   Tapia R., Han C., Sutton G., Sims D.;
RT   "Genome sequence of Bacillus cereus 03BB102.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Negative regulator of protease production and sporulation.
CC       {ECO:0000255|HAMAP-Rule:MF_01911}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01911}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001407; ACO28709.1; -; Genomic_DNA.
DR   RefSeq; WP_000834918.1; NZ_CP009318.1.
DR   AlphaFoldDB; C1EKG1; -.
DR   SMR; C1EKG1; -.
DR   EnsemblBacteria; ACO28709; ACO28709; BCA_1081.
DR   GeneID; 59157265; -.
DR   GeneID; 64200314; -.
DR   KEGG; bcx:BCA_1081; -.
DR   PATRIC; fig|572264.18.peg.1029; -.
DR   OMA; EKDWQNW; -.
DR   Proteomes; UP000002210; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01911; HTH_type_Hpr; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR023488; HTH_tscrpt_reg_Hpr.
DR   InterPro; IPR023187; Tscrpt_reg_MarR-type_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS01117; HTH_MARR_1; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Sporulation; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..185
FT                   /note="HTH-type transcriptional regulator Hpr"
FT                   /id="PRO_1000188793"
FT   DOMAIN          13..157
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01911"
FT   DNA_BIND        63..86
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01911"
SQ   SEQUENCE   185 AA;  21733 MW;  A5F01F355B557E89 CRC64;
     MKSGEKDYSV KEAMIFSQRI AQLSKALWKC VEKDWQMWIK PYDLNINEHH ILTIAYHLKG
     ASISEIAKFG VMHVSTAFNF SKKLEERGYL VFSKKEDDKR NTYIEITDKG EELLLRLMEE
     YDPENNSVFN GALALRNFYG KFPENIELIA ILRNIYGQDF IDIFEKSLED IEENFTESDQ
     KLVKK