ID   HPSE_SOYBN              Reviewed;          80 AA.
AC   P24337;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Hydrophobic seed protein;
DE            Short=HPS;
DE   AltName: Allergen=Gly m 1;
OS   Glycine max (Soybean) (Glycine hispida).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC   Glycine subgen. Soja.
OX   NCBI_TaxID=3847;
RN   [1]
RP   PROTEIN SEQUENCE, AND DISULFIDE BONDS.
RC   TISSUE=Seed;
RX   PubMed=3830151; DOI=10.1111/j.1432-1033.1987.tb10666.x;
RA   Odani S., Koide T., Ono T., Seto Y., Tanaka T.;
RT   "Soybean hydrophobic protein. Isolation, partial characterization and the
RT   complete primary structure.";
RL   Eur. J. Biochem. 162:485-491(1987).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS).
RX   PubMed=8515457; DOI=10.1006/jmbi.1993.1334;
RA   Baud F., Pebay-Peyroula E., Cohen-Addad C., Odani S., Lehmann M.S.;
RT   "Crystal structure of hydrophobic protein from soybean; a member of a new
RT   cysteine-rich family.";
RL   J. Mol. Biol. 231:877-887(1993).
CC   -!- TISSUE SPECIFICITY: Highly abundant in seeds.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC   -!- SIMILARITY: Belongs to the plant LTP family. PEARLI1 subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; A29385; A29385.
DR   PDB; 1HYP; X-ray; 1.80 A; A=1-80.
DR   PDBsum; 1HYP; -.
DR   AlphaFoldDB; P24337; -.
DR   SMR; P24337; -.
DR   STRING; 3847.GLYMA15G13750.1; -.
DR   Allergome; 368; Gly m 1.
DR   PRIDE; P24337; -.
DR   EvolutionaryTrace; P24337; -.
DR   Proteomes; UP000008827; Unplaced.
DR   Gene3D; 1.10.110.10; -; 1.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   InterPro; IPR027923; Hydrophob_seed_dom.
DR   Pfam; PF14547; Hydrophob_seed; 1.
DR   SUPFAM; SSF47699; SSF47699; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Allergen; Direct protein sequencing; Disulfide bond;
KW   Reference proteome.
FT   CHAIN           1..80
FT                   /note="Hydrophobic seed protein"
FT                   /id="PRO_0000153889"
FT   DISULFID        8..43
FT                   /evidence="ECO:0000269|PubMed:3830151"
FT   DISULFID        14..28
FT                   /evidence="ECO:0000269|PubMed:3830151"
FT   DISULFID        29..67
FT                   /evidence="ECO:0000269|PubMed:3830151"
FT   DISULFID        45..77
FT                   /evidence="ECO:0000269|PubMed:3830151"
FT   HELIX           12..19
FT                   /evidence="ECO:0007829|PDB:1HYP"
FT   HELIX           25..33
FT                   /evidence="ECO:0007829|PDB:1HYP"
FT   HELIX           37..50
FT                   /evidence="ECO:0007829|PDB:1HYP"
FT   HELIX           56..66
FT                   /evidence="ECO:0007829|PDB:1HYP"
SQ   SEQUENCE   80 AA;  8359 MW;  6BF40B553E24D636 CRC64;
     ALITRPSCPD LSICLNILGG SLGTVDDCCA LIGGLGDIEA IVCLCIQLRA LGILNLNRNL
     QLILNSCGRS YPSNATCPRT