ID   3SX1_MICCO              Reviewed;          84 AA.
AC   C6JUP1;
DT   26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 18.
DE   RecName: Full=Three-finger toxin 3FTx-1;
DE   Flags: Precursor;
OS   Micrurus corallinus (Brazilian coral snake).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Elapinae; Micrurus.
OX   NCBI_TaxID=54390;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=19291316; DOI=10.1186/1471-2164-10-112;
RA   Leao L.I., Ho P.L., Junqueira-de-Azevedo I.L.M.;
RT   "Transcriptomic basis for an antiserum against Micrurus corallinus (coral
RT   snake) venom.";
RL   BMC Genomics 10:112-112(2009).
RN   [2]
RP   PROTEIN SEQUENCE OF 22-36, IDENTIFICATION BY MASS SPECTROMETRY, AND
RP   SUBCELLULAR LOCATION.
RC   TISSUE=Venom;
RX   PubMed=21515432; DOI=10.1016/j.jprot.2011.04.003;
RA   Correa-Netto C., Junqueira-de-Azevedo Ide L., Silva D.A., Ho P.L.,
RA   Leitao-de-Araujo M., Alves M.L., Sanz L., Foguel D., Zingali R.B.,
RA   Calvete J.J.;
RT   "Snake venomics and venom gland transcriptomic analysis of Brazilian coral
RT   snakes, Micrurus altirostris and M. corallinus.";
RL   J. Proteomics 74:1795-1809(2011).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21515432}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC       subfamily. {ECO:0000305}.
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DR   EMBL; GQ139601; ACS74995.1; -; mRNA.
DR   AlphaFoldDB; C6JUP1; -.
DR   SMR; C6JUP1; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.60.10; -; 1.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   SUPFAM; SSF57302; SSF57302; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Glycoprotein; Secreted; Signal;
KW   Toxin.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000269|PubMed:21515432"
FT   CHAIN           22..84
FT                   /note="Three-finger toxin 3FTx-1"
FT                   /evidence="ECO:0000305|PubMed:21515432"
FT                   /id="PRO_0000422892"
FT   CARBOHYD        78
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        24..41
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        34..59
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        63..71
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        72..77
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
SQ   SEQUENCE   84 AA;  9311 MW;  370491854DC641CB CRC64;
     MKTLLLTLVV VTIVCLDLGN SLICYNTMMQ KVTCPEGKDK CEKYAVPVMR GKFYFSYQCT
     SKCHEGAYDV CCSTDLCNKS STSG