位置:首页 > 蛋白库 > HRCA_ACISJ
HRCA_ACISJ
ID   HRCA_ACISJ              Reviewed;         334 AA.
AC   A1W4H2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081}; OrderedLocusNames=Ajs_0905;
OS   Acidovorax sp. (strain JS42).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Acidovorax; unclassified Acidovorax.
OX   NCBI_TaxID=232721;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JS42;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.;
RT   "Complete sequence of chromosome 1 of Acidovorax sp. JS42.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC       dnaJ and groELS operons). Prevents heat-shock induction of these
CC       operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC   -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00081}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000539; ABM41147.1; -; Genomic_DNA.
DR   RefSeq; WP_011804349.1; NC_008782.1.
DR   AlphaFoldDB; A1W4H2; -.
DR   SMR; A1W4H2; -.
DR   STRING; 232721.Ajs_0905; -.
DR   EnsemblBacteria; ABM41147; ABM41147; Ajs_0905.
DR   KEGG; ajs:Ajs_0905; -.
DR   eggNOG; COG1420; Bacteria.
DR   HOGENOM; CLU_050019_0_0_4; -.
DR   OMA; DYPGTMG; -.
DR   Proteomes; UP000000645; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.390.60; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   HAMAP; MF_00081; HrcA; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR002571; HrcA.
DR   InterPro; IPR021153; HrcA_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   InterPro; IPR005104; WHTH_HrcA_DNA-bd.
DR   InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR   PANTHER; PTHR34824; PTHR34824; 1.
DR   Pfam; PF01628; HrcA; 1.
DR   Pfam; PF03444; HrcA_DNA-bdg; 1.
DR   PIRSF; PIRSF005485; HrcA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR00331; hrcA; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repressor; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..334
FT                   /note="Heat-inducible transcription repressor HrcA"
FT                   /id="PRO_1000118282"
SQ   SEQUENCE   334 AA;  36833 MW;  F4C2E714DC368E47 CRC64;
     MLDDRSKLLL KALVERYIAE GQPVGSRTLS RASGLELSPA TIRNVMADLE DLGLIASPHT
     SAGRVPTAKG YRLFVDTMLT VQQEQLPTVQ LMPEQPQKVI ANAAHLLSSL SQFVGVVMAP
     RRASVFRHIE FLRLSEKRFL VIIVSPDGDV QNRVIFTEVD YSQSQLVEAA NFLNANYAGL
     TMEQVRERLK LEVDKLRGEI AALMQAAVSV GSEAMSGSQD EVVFSGERNL LSVSDFSSNM
     SHLRRAFDLF EQKTQILRLL DISSRAEGVR IFIGGESQVV PFEELSVVSA PYEVDGQVVG
     TLGVIGPTRM SYDRMIQIVD ITSKLVSNAL SHRK
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024