ID   HRCA_BACCQ              Reviewed;         338 AA.
AC   B9IY83;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081}; OrderedLocusNames=BCQ_4102;
OS   Bacillus cereus (strain Q1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=361100;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Q1;
RX   PubMed=19060151; DOI=10.1128/jb.01629-08;
RA   Xiong Z., Jiang Y., Qi D., Lu H., Yang F., Yang J., Chen L., Sun L., Xu X.,
RA   Xue Y., Zhu Y., Jin Q.;
RT   "Complete genome sequence of the extremophilic Bacillus cereus strain Q1
RT   with industrial applications.";
RL   J. Bacteriol. 191:1120-1121(2009).
CC   -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC       dnaJ and groELS operons). Prevents heat-shock induction of these
CC       operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC   -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00081}.
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DR   EMBL; CP000227; ACM14529.1; -; Genomic_DNA.
DR   RefSeq; WP_000954950.1; NC_011969.1.
DR   AlphaFoldDB; B9IY83; -.
DR   SMR; B9IY83; -.
DR   EnsemblBacteria; ACM14529; ACM14529; BCQ_4102.
DR   GeneID; 64199661; -.
DR   KEGG; bcq:BCQ_4102; -.
DR   HOGENOM; CLU_050019_1_0_9; -.
DR   OMA; DYPGTMG; -.
DR   Proteomes; UP000000441; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.390.60; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   HAMAP; MF_00081; HrcA; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR002571; HrcA.
DR   InterPro; IPR021153; HrcA_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR   PANTHER; PTHR34824; PTHR34824; 1.
DR   Pfam; PF01628; HrcA; 1.
DR   PIRSF; PIRSF005485; HrcA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR00331; hrcA; 1.
PE   3: Inferred from homology;
KW   Repressor; Stress response; Transcription; Transcription regulation.
FT   CHAIN           1..338
FT                   /note="Heat-inducible transcription repressor HrcA"
FT                   /id="PRO_1000118289"
SQ   SEQUENCE   338 AA;  37855 MW;  A4054A964BCD724F CRC64;
     MLTERQLLIL QTIIDDFIGS AQPVGSRTLA KKDEITFSSA TIRNEMADLE ELGFIEKTHS
     SSGRVPSEKG YRFYVDHLLA PQNLPNDEIV QIKDLFAERI FEAEKIAQQS AQILSELTNY
     TAIVLGPKLS TNKLKNVQIV PLDRQTAVAI IVTDTGHVQS KTITVPESVD LSDLEKMVNI
     LNEKLSGVPM SELHNKIFKE IVTVLRGYVH NYDSAIKILD GTFQVPLSEK IYFGGKANML
     SQPEFHDIQK VRSLLTMIDN EAEFYDILRH KQVGIQVKIG RENSATAMED CSLISATYSI
     GEEQLGTIAI LGPTRMQYSR VISLLQLFTR QITDGLKK