ID   HRCA_CHLL3              Reviewed;         357 AA.
AC   Q3B2T3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081}; OrderedLocusNames=Plut_1489;
OS   Chlorobium luteolum (strain DSM 273 / BCRC 81028 / 2530) (Pelodictyon
OS   luteolum).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Chlorobium/Pelodictyon group; Pelodictyon.
OX   NCBI_TaxID=319225;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 273 / BCRC 81028 / 2530;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Pelodictyon luteolum DSM 273.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC       dnaJ and groELS operons). Prevents heat-shock induction of these
CC       operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC   -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00081}.
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DR   EMBL; CP000096; ABB24348.1; -; Genomic_DNA.
DR   RefSeq; WP_011358220.1; NC_007512.1.
DR   AlphaFoldDB; Q3B2T3; -.
DR   SMR; Q3B2T3; -.
DR   STRING; 319225.Plut_1489; -.
DR   EnsemblBacteria; ABB24348; ABB24348; Plut_1489.
DR   KEGG; plt:Plut_1489; -.
DR   eggNOG; COG1420; Bacteria.
DR   HOGENOM; CLU_050019_1_0_10; -.
DR   OMA; DYPGTMG; -.
DR   OrthoDB; 1510750at2; -.
DR   Proteomes; UP000002709; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.390.60; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   HAMAP; MF_00081; HrcA; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR002571; HrcA.
DR   InterPro; IPR021153; HrcA_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR   PANTHER; PTHR34824; PTHR34824; 1.
DR   Pfam; PF01628; HrcA; 1.
DR   PIRSF; PIRSF005485; HrcA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR00331; hrcA; 1.
PE   3: Inferred from homology;
KW   Repressor; Stress response; Transcription; Transcription regulation.
FT   CHAIN           1..357
FT                   /note="Heat-inducible transcription repressor HrcA"
FT                   /id="PRO_1000010441"
SQ   SEQUENCE   357 AA;  39849 MW;  28A2C3E401082B26 CRC64;
     MGSRELNLRE RQVLGIIIQL YVVTAAPVGS RYIARNYSLG LSDATIRNVM ADLEAEGYIS
     QPHTSAGRIP TDLGYRYYVD LIMKVQRIDE EEKRRMESDF GPISMEGRGT SAEVLVSAAK
     VLGSISRQLS VVLSPTLSNA VFEKLDMVLL SSTRMMVVLS IQSMFVKTIV MELQHELTRQ
     KVDEVVDLLN ERLSGLTLSE IRRSITRRLA GSSCDTNLKD LIVRSADSLF DESPIFERLY
     ISGAEYIVEQ PEFKQPERVR ELITMIEDKF SVARLVEDIA PKQDLKRTAG HDVSISIGRE
     NSALQAEDLT IVSAPYYAGS MVGTLGILGP KRMDYEHAVR VLNYMADCLT ATLSDVN