HRCA_CHLP8
ID HRCA_CHLP8 Reviewed; 356 AA.
AC B3QPX0;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081}; OrderedLocusNames=Cpar_1575;
OS Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) (Chlorobium vibrioforme
OS subsp. thiosulfatophilum).
OC Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum.
OX NCBI_TaxID=517417;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 263 / NCIMB 8327;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Zhao F., Li T., Liu Z., Overmann J.,
RA Bryant D.A., Richardson P.;
RT "Complete sequence of Chlorobaculum parvum NCIB 8327.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC dnaJ and groELS operons). Prevents heat-shock induction of these
CC operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC Rule:MF_00081}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001099; ACF11973.1; -; Genomic_DNA.
DR RefSeq; WP_012502806.1; NC_011027.1.
DR AlphaFoldDB; B3QPX0; -.
DR SMR; B3QPX0; -.
DR STRING; 517417.Cpar_1575; -.
DR EnsemblBacteria; ACF11973; ACF11973; Cpar_1575.
DR KEGG; cpc:Cpar_1575; -.
DR eggNOG; COG1420; Bacteria.
DR HOGENOM; CLU_050019_1_0_10; -.
DR OMA; DYPGTMG; -.
DR OrthoDB; 1510750at2; -.
DR Proteomes; UP000008811; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 3.30.390.60; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR HAMAP; MF_00081; HrcA; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR002571; HrcA.
DR InterPro; IPR021153; HrcA_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR PANTHER; PTHR34824; PTHR34824; 1.
DR Pfam; PF01628; HrcA; 1.
DR PIRSF; PIRSF005485; HrcA; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR TIGRFAMs; TIGR00331; hrcA; 1.
PE 3: Inferred from homology;
KW Repressor; Stress response; Transcription; Transcription regulation.
FT CHAIN 1..356
FT /note="Heat-inducible transcription repressor HrcA"
FT /id="PRO_1000092802"
SQ SEQUENCE 356 AA; 39129 MW; BBC89237E82BE079 CRC64;
MLYRDLTLRE RQVLGIIIQS FVVSATPVGS RTIARNYNLG LSDATIRNVM ADLEADGFIS
QPHTSAGRVP TDKGYRYYVD LLMNVSGIDE QEKQMIDARF STRSSELKGT SAEVLGAAAK
VLGSISRQLG VVLPPRLSNA VFERLDIVQL ASTRIMVVIA IQSLFVKTIV MELTAEISRQ
KIDDVVNILN ERLSGLTLEE IRSTIGKRLS DCQSREGLMN SIVGAADTLF DESSILDRLY
VSGTENIVDQ PEFKQPQKVR NIITMIEDKF GIARLVDNAL PSGAYQGRDR EVAISIGTEN
RTDNAIDLTI VSSPYYAGKM VGKVGIMGPK RMDYEHAVRV VNYMAGCLSE ALSGNN