ID   AP1_ARALL               Reviewed;         256 AA.
AC   D7KWY6;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   10-AUG-2010, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Floral homeotic protein APETALA 1;
DE   AltName: Full=Agamous-like MADS-box protein AP1;
GN   Name=AP1; ORFNames=ARALYDRAFT_476039;
OS   Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=81972;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MN47;
RX   PubMed=21478890; DOI=10.1038/ng.807;
RA   Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA   Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA   Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA   Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA   Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA   Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT   "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT   change.";
RL   Nat. Genet. 43:476-481(2011).
CC   -!- FUNCTION: Transcription factor that promotes early floral meristem
CC       identity in synergy with LEAFY. Displays a redundant function with
CC       CAULIFLOWER in the up-regulation of LEAFY. Required subsequently for
CC       the transition of an inflorescence meristem into a floral meristem, and
CC       for the normal development of sepals and petals in flowers. Regulates
CC       positively B class homeotic proteins (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer capable of binding to CArG-box sequences.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
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DR   EMBL; GL348714; EFH64962.1; -; Genomic_DNA.
DR   RefSeq; XP_002888703.1; XM_002888657.1.
DR   AlphaFoldDB; D7KWY6; -.
DR   SMR; D7KWY6; -.
DR   STRING; 81972.D7KWY6; -.
DR   EnsemblPlants; fgenesh2_kg.2__1169__AT1G69120.1; fgenesh2_kg.2__1169__AT1G69120.1; fgenesh2_kg.2__1169__AT1G69120.1.
DR   Gramene; fgenesh2_kg.2__1169__AT1G69120.1; fgenesh2_kg.2__1169__AT1G69120.1; fgenesh2_kg.2__1169__AT1G69120.1.
DR   eggNOG; KOG0014; Eukaryota.
DR   HOGENOM; CLU_053053_0_2_1; -.
DR   OrthoDB; 1178730at2759; -.
DR   Proteomes; UP000008694; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:EnsemblPlants.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0010582; P:floral meristem determinacy; IEA:EnsemblPlants.
DR   GO; GO:0009933; P:meristem structural organization; IEA:EnsemblPlants.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; -; 1.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002487; TF_Kbox.
DR   InterPro; IPR002100; TF_MADSbox.
DR   InterPro; IPR036879; TF_MADSbox_sf.
DR   Pfam; PF01486; K-box; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SSF55455; 1.
DR   PROSITE; PS51297; K_BOX; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   3: Inferred from homology;
KW   Activator; Coiled coil; Developmental protein; Differentiation;
KW   DNA-binding; Flowering; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..256
FT                   /note="Floral homeotic protein APETALA 1"
FT                   /id="PRO_0000417129"
FT   DOMAIN          1..61
FT                   /note="MADS-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT   DOMAIN          88..178
FT                   /note="K-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
FT   REGION          184..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   256 AA;  30217 MW;  4B765829393E51CE CRC64;
     MGRGRVQLKR IENKINRQVT FSKRRAGLLK KAHEISVLCD AEVALVVFSH KGKLFEYSTD
     SCMEKILERY ERYSYAERQL IAPESDVNTN WSMEYNRLKA KIELLERNQR HYLGEDLNAM
     SPKELQNLEQ QLDTALKHIR TRKNQLMYES INELQRKEKA IQEQNSMLSK QIKEREKILR
     AQQEQWDQQN HGHNMPPPPP PQQHQIQHPY MLSHQPSPFL NMGGLYQEED PMAMRRNELE
     LTLEPVYNCN LGCFAA