AP1_BRARP
ID AP1_BRARP Reviewed; 256 AA.
AC P0DI14;
DT 16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2012, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Floral homeotic protein APETALA 1;
DE Short=BcpAP1;
DE AltName: Full=Agamous-like MADS-box protein AP1;
GN Name=AP1;
OS Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=51351;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Chiifu;
RA Kwon S.J., Kim J.A., Mun J.H., Park T.H., Hong J.K., Kim J.S., Jin M.,
RA Lim M.H., Lee S.C., Seol Y.J., Lee S.I., Yang T.J., Park J.Y., Park B.S.;
RT "Shotgun sequence of a Brassica rapa BAC clone.";
RL Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor that promotes early floral meristem
CC identity in synergy with LEAFY. Displays a redundant function with
CC CAULIFLOWER in the up-regulation of LEAFY. Required subsequently for
CC the transition of an inflorescence meristem into a floral meristem, and
CC for the normal development of sepals and petals in flowers. Regulates
CC positively B class homeotic proteins (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer capable of binding to CArG-box sequences.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
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DR EMBL; AC189458; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P0DI14; -.
DR SMR; P0DI14; -.
DR STRING; 51351.P0DI14; -.
DR eggNOG; KOG0014; Eukaryota.
DR InParanoid; P0DI14; -.
DR Proteomes; UP000011750; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0010582; P:floral meristem determinacy; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 3: Inferred from homology;
KW Activator; Coiled coil; Developmental protein; Differentiation;
KW DNA-binding; Flowering; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..256
FT /note="Floral homeotic protein APETALA 1"
FT /id="PRO_0000417137"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 88..178
FT /note="K-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
FT REGION 180..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 256 AA; 30176 MW; A8064493C6BD0FC0 CRC64;
MGRGRVQLKR IENKINRQVT FSKRRAGLFK KAHEISVLCD AEVALVVFSH KGKLFEYSTD
SCMEKILERY ERYSYAERQL IAPESDVNTN WSMEYNRLKA KIELLERNQR HYLGEDLQAM
SPKELQNLEQ QLDTALKHIR SRKNQLMYDS VNELQRKEKA IQEQNSMLSK QIKEREKVLR
AQQEQWDQQN HGQNMPPPPP PQEHQIQHPY MLSHQPSPFL NMGGLYEEED PMAMRRNDLD
LSLEPVYNCN LGCFAS