ID   HRCA_PHYAS              Reviewed;         340 AA.
AC   B1VAB8;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081}; OrderedLocusNames=PA0557;
OS   Phytoplasma australiense.
OC   Bacteria; Tenericutes; Mollicutes; Acholeplasmatales; Acholeplasmataceae;
OC   Candidatus Phytoplasma; 16SrXII (Stolbur group).
OX   NCBI_TaxID=59748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18359806; DOI=10.1128/jb.01301-07;
RA   Tran-Nguyen L.T., Kube M., Schneider B., Reinhardt R., Gibb K.S.;
RT   "Comparative genome analysis of 'Candidatus Phytoplasma australiense'
RT   (subgroup tuf-Australia I; rp-A) and 'Ca. Phytoplasma asteris' strains OY-M
RT   and AY-WB.";
RL   J. Bacteriol. 190:3979-3991(2008).
CC   -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC       dnaJ and groELS operons). Prevents heat-shock induction of these
CC       operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC   -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00081}.
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DR   EMBL; AM422018; CAM11891.1; -; Genomic_DNA.
DR   RefSeq; WP_012359029.1; NC_010544.1.
DR   AlphaFoldDB; B1VAB8; -.
DR   SMR; B1VAB8; -.
DR   STRING; 59748.PA0557; -.
DR   EnsemblBacteria; CAM11891; CAM11891; PA0557.
DR   KEGG; pal:PA0557; -.
DR   eggNOG; COG1420; Bacteria.
DR   OMA; DYPGTMG; -.
DR   Proteomes; UP000008323; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.390.60; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   HAMAP; MF_00081; HrcA; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR002571; HrcA.
DR   InterPro; IPR021153; HrcA_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR   PANTHER; PTHR34824; PTHR34824; 1.
DR   Pfam; PF01628; HrcA; 1.
DR   PIRSF; PIRSF005485; HrcA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR00331; hrcA; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repressor; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..340
FT                   /note="Heat-inducible transcription repressor HrcA"
FT                   /id="PRO_1000117111"
SQ   SEQUENCE   340 AA;  38931 MW;  0FCC92FE47DAD05F CRC64;
     MLSDRKKIIL KAVVESYSQK RQPVGSKSLI HLPELQFSSA TIRYDMLKLE EEGFLKKNHT
     SSGRIPSFKG YTYYLTHLLT RDYDAANSFP LIDKVIQNKT FHKNKVIKEA IKLLNSLTSY
     TAMAIGPDVF NNSKISKIDF IPLNHKQALI LIITNKGDVQ HQNISLDQTK EISIYDLKDI
     VKIISDLLVG KYLSEAVKII QSDFVKQTIA KYIRFQEQLI ALFIEAFSSF ASENTYFAGI
     SEMTKKKEFS DLELIKKIMN LLERKELLKI LLNQEGLSFK LSDELQLTPV KDYMILSIPF
     AIDANEKGTI AILGPSWMKY PKIIPLLEYL SIHLSKLNQE