ID   AP1_CITSI               Reviewed;         256 AA.
AC   A2IB53;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Floral homeotic protein APETALA 1;
DE   AltName: Full=Agamous-like MADS-box protein AP1;
DE            Short=CitMAD AP1;
GN   Name=AP1;
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Liu Y.Z., Ye J.L., Zhang J.C., Li D.L., Deng X.X.;
RT   "Isolating a citrus MADs-box gene related with fruit ripening and floral
RT   development.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcription factor that promotes early floral meristem
CC       identity in synergy with LEAFY. Displays a redundant function with
CC       CAULIFLOWER in the up-regulation of LEAFY. Required subsequently for
CC       the transition of an inflorescence meristem into a floral meristem, and
CC       for the normal development of sepals and petals in flowers. Regulates
CC       positively B class homeotic proteins (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer capable of binding to CArG-box sequences.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
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DR   EMBL; EF185417; ABM67697.1; -; mRNA.
DR   AlphaFoldDB; A2IB53; -.
DR   SMR; A2IB53; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; -; 1.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002487; TF_Kbox.
DR   InterPro; IPR002100; TF_MADSbox.
DR   InterPro; IPR036879; TF_MADSbox_sf.
DR   Pfam; PF01486; K-box; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SSF55455; 1.
DR   PROSITE; PS51297; K_BOX; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   2: Evidence at transcript level;
KW   Activator; Coiled coil; Developmental protein; Differentiation;
KW   DNA-binding; Flowering; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..256
FT                   /note="Floral homeotic protein APETALA 1"
FT                   /id="PRO_0000417138"
FT   DOMAIN          1..61
FT                   /note="MADS-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT   DOMAIN          88..178
FT                   /note="K-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
SQ   SEQUENCE   256 AA;  30425 MW;  FF16364316A8BED0 CRC64;
     MGRGRVQLKR IENKINRQVT FSKRRAGLLK KAHEISVLCD AEVALVVFSH KGKLFEYSTD
     SCMEKILERY ERYSYAERQL IAPESDVNTN WSMEYNRLKA KIELLERNQR HYLGEDLQAM
     SPKELQNLEQ QLDTALKHIR TRKNQLMYES INELQKKEKA IQEQNSMLFK QIKEREKIFR
     AQQEQWDQQN QGPNMPPPLP PQQHQIQHPY MLFHQPFPFF NMGGLYQEDD PMAMRRNDLE
     LTFEPVYNCN LGCFAA