ID   HRCA_RHOPB              Reviewed;         362 AA.
AC   Q21CI5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081}; OrderedLocusNames=RPC_0326;
OS   Rhodopseudomonas palustris (strain BisB18).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316056;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BisB18;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S.,
RA   Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB18.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC       dnaJ and groELS operons). Prevents heat-shock induction of these
CC       operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC   -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00081}.
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DR   EMBL; CP000301; ABD85901.1; -; Genomic_DNA.
DR   RefSeq; WP_011470809.1; NC_007925.1.
DR   AlphaFoldDB; Q21CI5; -.
DR   SMR; Q21CI5; -.
DR   STRING; 316056.RPC_0326; -.
DR   EnsemblBacteria; ABD85901; ABD85901; RPC_0326.
DR   KEGG; rpc:RPC_0326; -.
DR   eggNOG; COG1420; Bacteria.
DR   HOGENOM; CLU_050019_0_0_5; -.
DR   OMA; DYPGTMG; -.
DR   OrthoDB; 1510750at2; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.390.60; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   HAMAP; MF_00081; HrcA; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR002571; HrcA.
DR   InterPro; IPR021153; HrcA_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR   PANTHER; PTHR34824; PTHR34824; 1.
DR   Pfam; PF01628; HrcA; 1.
DR   PIRSF; PIRSF005485; HrcA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR00331; hrcA; 1.
PE   3: Inferred from homology;
KW   Repressor; Stress response; Transcription; Transcription regulation.
FT   CHAIN           1..362
FT                   /note="Heat-inducible transcription repressor HrcA"
FT                   /id="PRO_1000010444"
SQ   SEQUENCE   362 AA;  38895 MW;  862B18D32A1D01A4 CRC64;
     MAHHDPIGLI APNAGLAQLN ERSREIFRQI VESYLATGEP VGSRNISRLI TVPLSPASVR
     NVMSDLEQLG LIYAPHTSAG RLPTELGLRF FVDALMQVGD LTEPERQSIQ AQLASVGRAQ
     SVEAALGEAL TRLSGLTRAA AVVLTAKSNA RLKHIEFVRL EPERALVVLV SEDGQVENRV
     LTLAAGVPSS ALIEASNFLN ARIRGRTLAE ARLELETALS QDRAELDQLT QKVISAGIAS
     WSGGANDDRQ LIVRGHANLL EDLHALDDLE RVRLLFDDLE TKRGVIDLLG RAESAEGVRI
     FIGSENKLFS LSGSSTIIAP YSDGAGHIVG VLGVIGPTRL NYARVIPMVD YAARVVSQML
     GG