ID   HRCA_SYNE7              Reviewed;         353 AA.
AC   Q31QM1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   OrderedLocusNames=Synpcc7942_0616;
OS   Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS   R2).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=1140;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC       dnaJ and groELS operons). Prevents heat-shock induction of these
CC       operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC   -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00081}.
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DR   EMBL; CP000100; ABB56648.1; -; Genomic_DNA.
DR   RefSeq; WP_011243220.1; NC_007604.1.
DR   AlphaFoldDB; Q31QM1; -.
DR   SMR; Q31QM1; -.
DR   STRING; 1140.Synpcc7942_0616; -.
DR   PRIDE; Q31QM1; -.
DR   EnsemblBacteria; ABB56648; ABB56648; Synpcc7942_0616.
DR   KEGG; syf:Synpcc7942_0616; -.
DR   eggNOG; COG1420; Bacteria.
DR   HOGENOM; CLU_050019_2_0_3; -.
DR   OMA; DYPGTMG; -.
DR   OrthoDB; 1510750at2; -.
DR   BioCyc; SYNEL:SYNPCC7942_0616-MON; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.390.60; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   HAMAP; MF_00081; HrcA; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR002571; HrcA.
DR   InterPro; IPR021153; HrcA_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR   PANTHER; PTHR34824; PTHR34824; 1.
DR   Pfam; PF01628; HrcA; 1.
DR   PIRSF; PIRSF005485; HrcA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR00331; hrcA; 1.
PE   3: Inferred from homology;
KW   Repressor; Stress response; Transcription; Transcription regulation.
FT   CHAIN           1..353
FT                   /note="Heat-inducible transcription repressor HrcA"
FT                   /id="PRO_1000010470"
SQ   SEQUENCE   353 AA;  38806 MW;  54379761C9C48F98 CRC64;
     MLVSRLTARQ QTILSATVRH YVRTAEPVGS KALAEQYGLS VSAATIRNAM GVLERAGLLY
     QPHTSAGRVP SEGGYRLYVD QLMEPDRALQ RQTEQQLSQQ LPDRRQSLEA LLRGAAQILA
     SLSGYLSLIT FPLGLEFQVR HLQLVAIAPH QVLLIVVNDS YETQSALLTL PELDRDLEAD
     QLDRQLLLLS NFLNQELQGR SLQALANLDW PVLGSELQSL AGILQQGLQD LEKRWQPTPA
     TSLLVCGLAD LLRQPEFNEL QQVQALLELL EGEQTQLLPL MLADPAADQV RVRIGSELPL
     APIRSCSLVS AFYCREQQPV GSVSLIGPTR MLYENAVAAV EATASYLSEA IAS