ID   HRCA_SYNS9              Reviewed;         324 AA.
AC   Q3AW12;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   OrderedLocusNames=Syncc9902_2097;
OS   Synechococcus sp. (strain CC9902).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=316279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC9902;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Synechococcus sp. CC9902.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC       dnaJ and groELS operons). Prevents heat-shock induction of these
CC       operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC   -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00081}.
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DR   EMBL; CP000097; ABB27055.1; -; Genomic_DNA.
DR   RefSeq; WP_011360839.1; NC_007513.1.
DR   AlphaFoldDB; Q3AW12; -.
DR   SMR; Q3AW12; -.
DR   STRING; 316279.Syncc9902_2097; -.
DR   EnsemblBacteria; ABB27055; ABB27055; Syncc9902_2097.
DR   KEGG; sye:Syncc9902_2097; -.
DR   eggNOG; COG1420; Bacteria.
DR   HOGENOM; CLU_050019_1_0_3; -.
DR   OMA; DYPGTMG; -.
DR   OrthoDB; 1510750at2; -.
DR   Proteomes; UP000002712; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.390.60; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   HAMAP; MF_00081; HrcA; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR002571; HrcA.
DR   InterPro; IPR021153; HrcA_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR   PANTHER; PTHR34824; PTHR34824; 1.
DR   Pfam; PF01628; HrcA; 1.
DR   PIRSF; PIRSF005485; HrcA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR00331; hrcA; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repressor; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..324
FT                   /note="Heat-inducible transcription repressor HrcA"
FT                   /id="PRO_1000010473"
SQ   SEQUENCE   324 AA;  35502 MW;  04ABA6C88C7220E6 CRC64;
     MKPLSRRQEQ VLQATVHHYV DTMEPVGSRT LVQRFSMPAS SATIRSAMGA LEQRGLLTQP
     HTSSGRIPSA LGYRHYVDCL LPEPAATVLH LERELTGLSL GWAALDDLLL QLARRLTDFT
     GLMSLITRPT RTQPQLAAIR LVQSGERLLV MLVENSGHAS HLNLRLPHAT SDELDAIERW
     AEQQLRGGAL NWEKLPTQLQ RSGDVLRHAL EHPSISAEPT TLVHGLSRLV AEPEFQSAQD
     LGPLLQLIDD EPMALISPGA EARVLIGQEH PQSALEACSV VQAPYRCGQE GTGHIALIGP
     MRMAYATACS AVERVARHLE LLLS