AP21_ORYSI
ID AP21_ORYSI Reviewed; 512 AA.
AC B8AXC3; A6N140;
DT 16-JAN-2019, integrated into UniProtKB/Swiss-Prot.
DT 16-JAN-2019, sequence version 2.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=APETALA2-like protein 1 {ECO:0000305};
GN Name=AP2-1 {ECO:0000305}; ORFNames=OsI_18248 {ECO:0000312|EMBL:EEC78421.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 341-512 (ISOFORM 1).
RC TISSUE=Shoot;
RA Kumari S., Panjabi V., Singla-Pareek S.L., Sopory S.K., Pareek A.;
RT "A comparative transcriptome map of early and late salinity stress
RT responses in contrasting genotypes of Oryza sativa L.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transcription factor (By similarity). Involved in
CC spikelet transition. Regulator of starch biosynthesis especially during
CC seed development (e.g. endosperm starch granules); represses the
CC expression of type I starch synthesis genes. Prevents lemma and palea
CC elongation as well as grain growth (By similarity).
CC {ECO:0000250|UniProtKB:P47927, ECO:0000250|UniProtKB:Q2TQ34}.
CC -!- SUBUNIT: May form homodimer (By similarity). Interacts with TPR2/ASP1
CC (By similarity). {ECO:0000250|UniProtKB:P47927,
CC ECO:0000250|UniProtKB:Q2TQ34}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=B8AXC3-1; Sequence=Displayed;
CC Name=2;
CC IsoId=B8AXC3-2; Sequence=VSP_059994;
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. AP2
CC subfamily. {ECO:0000305}.
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DR EMBL; CM000130; EEC78421.1; -; Genomic_DNA.
DR EMBL; EF576372; ABR25960.1; -; mRNA.
DR AlphaFoldDB; B8AXC3; -.
DR SMR; B8AXC3; -.
DR STRING; 39946.B8AXC3; -.
DR EnsemblPlants; BGIOSGA018911-TA; BGIOSGA018911-PA; BGIOSGA018911. [B8AXC3-2]
DR Gramene; BGIOSGA018911-TA; BGIOSGA018911-PA; BGIOSGA018911. [B8AXC3-2]
DR HOGENOM; CLU_035462_0_0_1; -.
DR OMA; KASCNSN; -.
DR Proteomes; UP000007015; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:EnsemblPlants.
DR GO; GO:2000014; P:regulation of endosperm development; IEA:EnsemblPlants.
DR GO; GO:0009909; P:regulation of flower development; IEA:EnsemblPlants.
DR GO; GO:0080050; P:regulation of seed development; IEA:EnsemblPlants.
DR GO; GO:0010581; P:regulation of starch biosynthetic process; IEA:EnsemblPlants.
DR CDD; cd00018; AP2; 2.
DR Gene3D; 3.30.730.10; -; 2.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 2.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 2.
DR SUPFAM; SSF54171; SSF54171; 2.
DR PROSITE; PS51032; AP2_ERF; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..512
FT /note="APETALA2-like protein 1"
FT /id="PRO_0000445988"
FT DNA_BIND 171..227
FT /note="AP2/ERF 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT DNA_BIND 263..320
FT /note="AP2/ERF 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 159..168
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT MOTIF 341..345
FT /note="EAR"
FT /evidence="ECO:0000250|UniProtKB:P47927"
FT COMPBIAS 23..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..62
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..156
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 380
FT /note="K -> KASCNS (in isoform 2)"
FT /id="VSP_059994"
FT CONFLICT 344
FT /note="S -> R (in Ref. 2; ABR25960)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 512 AA; 55567 MW; 21A85A01422B28EF CRC64;
MELDLNNVAE GVVEKHETAA RSDSGTSESS VLNGEASGAA TTPAEEGSSS TPPPPPPPPA
AVLEFSILRS SASASGENDA DDDEEEEATP SPPPHHQHQQ LLVTRELFPS AAPSPQHWAE
LGFLRPDPPR PHPDIRILAH APPPAPPPPP PQPQPQAAKK SRRGPRSRSS QYRGVTFYRR
TGRWESHIWD CGKQVYLGGF DTAHAAARAY DRAAIKFRGV EADINFNLSD YEEDMRQMKS
LSKEEFVHVL RRQSTGFSRG SSKYRGVTLH KCGRWEARMG QFLGKKYIYL GLFDSEVEAA
RAYDKAAIKC NGREAVTNFE PSTYDGELPT DAAAQGADVD LNLSISQPAA SQQSPKRDSG
SLGLQIHHGS FEGSEFKRAK NDAAPSELAS RPHRFPLLTE HPPIWTAQPH PLFPNNEDAS
RSSDQKRKPS EGVAVPSWAW KQVSHHHPAP PHTLPLPFFS SSSSSPSSSS AAASSGFSKA
ATTAAAAQHT ATLRFDPTAP SSSSSSRHHH HH
