ID   HRCR_ERWAM              Reviewed;         217 AA.
AC   Q46646;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 2.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Harpin secretion protein HrcR;
GN   Name=hrcR;
OS   Erwinia amylovora (Fire blight bacteria).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=552;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=321;
RX   PubMed=8626302; DOI=10.1128/jb.178.6.1720-1730.1996;
RA   Bogdanove A.J., Wei Z.-M., Zhao L., Beer S.V.;
RT   "Erwinia amylovora secretes harpin via a type III pathway and contains a
RT   homolog of yopN of Yersinia spp.";
RL   J. Bacteriol. 178:1720-1730(1996).
RN   [2]
RP   SEQUENCE REVISION.
RA   Beer S.V.;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the secretion of harpin.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FliP/MopC/SpaP family. {ECO:0000305}.
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DR   EMBL; L25828; AAB06005.2; -; Genomic_DNA.
DR   RefSeq; WP_004155342.1; NZ_RQKG01000002.1.
DR   AlphaFoldDB; Q46646; -.
DR   SMR; Q46646; -.
DR   GeneID; 8913097; -.
DR   OMA; GMQMVSP; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR005838; T3SS_IM_P.
DR   InterPro; IPR005773; YopR.
DR   PANTHER; PTHR30587; PTHR30587; 1.
DR   Pfam; PF00813; FliP; 1.
DR   PRINTS; PR01302; TYPE3IMPPROT.
DR   TIGRFAMs; TIGR01102; yscR; 1.
DR   PROSITE; PS01060; FLIP_1; 1.
DR   PROSITE; PS01061; FLIP_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Hypersensitive response elicitation; Membrane;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..217
FT                   /note="Harpin secretion protein HrcR"
FT                   /id="PRO_0000191995"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   217 AA;  24192 MW;  223DB56B96D9B510 CRC64;
     MNTEQFDPMT FALFLGALSL IPMLMIVCTC FLKISMVLLI TRNAIGVQQV PPNMALYGIA
     LAATLFVMAP VFNQMQQQFS QVPADLSSMD NLKTSVTNGV APLQKFMTHN TDPDILIHLQ
     ENSVRMWPKE MSDSVNKDNL LLVIPAFVLS ELQAGFKIGF LIYIPFIVID LIVSNVLLAL
     GMQMVAPMTL SLPLKMLLFV LINGWTRLLD GLFYSYL