ID   HRCR_RALSO              Reviewed;         217 AA.
AC   Q52488;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Hypersensitivity response secretion protein HrcR;
GN   Name=hrcR; Synonyms=hrpT; OrderedLocusNames=RSp0860; ORFNames=RS01631;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OG   Plasmid megaplasmid Rsp.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=7623665; DOI=10.1111/j.1365-2958.1995.tb02284.x;
RA   van Gijsegem F., Gough C.L., Zischek C., Niqueux E., Arlat M., Genin S.,
RA   Barberis P., German S., Castello P., Boucher C.A.;
RT   "The hrp gene locus of Pseudomonas solanacearum, which controls the
RT   production of a type III secretion system, encodes eight proteins related
RT   to components of the bacterial flagellar biogenesis complex.";
RL   Mol. Microbiol. 15:1095-1114(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- FUNCTION: Involved in the secretion of PopA, a proteinaceous elicitor
CC       of the hypersensitivity response in plants.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FliP/MopC/SpaP family. {ECO:0000305}.
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DR   EMBL; AJ245811; CAB58247.1; -; Genomic_DNA.
DR   EMBL; AL646053; CAD18011.1; -; Genomic_DNA.
DR   PIR; S61851; S61851.
DR   RefSeq; WP_011004157.1; NC_003296.1.
DR   AlphaFoldDB; Q52488; -.
DR   SMR; Q52488; -.
DR   STRING; 267608.RSp0860; -.
DR   EnsemblBacteria; CAD18011; CAD18011; RSp0860.
DR   GeneID; 60503768; -.
DR   KEGG; rso:RSp0860; -.
DR   eggNOG; COG4790; Bacteria.
DR   HOGENOM; CLU_042028_2_0_4; -.
DR   OMA; IMITCFP; -.
DR   Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR005838; T3SS_IM_P.
DR   InterPro; IPR005773; YopR.
DR   PANTHER; PTHR30587; PTHR30587; 1.
DR   Pfam; PF00813; FliP; 1.
DR   PRINTS; PR01302; TYPE3IMPPROT.
DR   TIGRFAMs; TIGR01102; yscR; 1.
DR   PROSITE; PS01060; FLIP_1; 1.
DR   PROSITE; PS01061; FLIP_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Hypersensitive response elicitation; Membrane; Plasmid;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..217
FT                   /note="Hypersensitivity response secretion protein HrcR"
FT                   /id="PRO_0000191997"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   217 AA;  23739 MW;  79745499E2E2D80A CRC64;
     MQNVEFASLI VMAVAIALLP FAAMVVTSYT KIVVVLGLLR NALGVQQVPP NMVLNGIAMI
     VSCFVMAPVG MEAMQRAHVQ INAQGGTNIT QVMPLLDAAR DPFREFLNKH TNAREKAFFM
     RSAQQLWPPA KAAQLKDDDL IVLAPAFTLT ELTSAFRIGF LLYLAFIVID LVIANLLMAL
     GLSQVTPSNV AIPFKLLLFV VMDGWSVLIH GLVNTYR