HRCT1_MOUSE
ID HRCT1_MOUSE Reviewed; 109 AA.
AC Q9D6B9; A2ANK5;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 2.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Histidine-rich carboxyl terminus protein 1;
GN Name=Hrct1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Placenta;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AK014425; BAB29342.1; -; mRNA.
DR EMBL; AL824712; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS51169.1; -.
DR RefSeq; NP_081787.1; NM_027511.1.
DR AlphaFoldDB; Q9D6B9; -.
DR SMR; Q9D6B9; -.
DR STRING; 10090.ENSMUSP00000092727; -.
DR PaxDb; Q9D6B9; -.
DR PRIDE; Q9D6B9; -.
DR Antibodypedia; 78136; 4 antibodies from 4 providers.
DR Ensembl; ENSMUST00000095109; ENSMUSP00000092727; ENSMUSG00000071001.
DR GeneID; 100039781; -.
DR KEGG; mmu:100039781; -.
DR UCSC; uc008sqx.1; mouse.
DR CTD; 646962; -.
DR MGI; MGI:1917945; Hrct1.
DR VEuPathDB; HostDB:ENSMUSG00000071001; -.
DR eggNOG; ENOG502SX6E; Eukaryota.
DR GeneTree; ENSGT00510000049544; -.
DR HOGENOM; CLU_177134_0_0_1; -.
DR InParanoid; Q9D6B9; -.
DR OMA; ATCLFHG; -.
DR BioGRID-ORCS; 100039781; 0 hits in 71 CRISPR screens.
DR ChiTaRS; Hrct1; mouse.
DR PRO; PR:Q9D6B9; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q9D6B9; protein.
DR Bgee; ENSMUSG00000071001; Expressed in interventricular septum and 79 other tissues.
DR Genevisible; Q9D6B9; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR031506; HRCT1.
DR PANTHER; PTHR23009; PTHR23009; 1.
DR Pfam; PF15758; HRCT1; 1.
PE 4: Predicted;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..109
FT /note="Histidine-rich carboxyl terminus protein 1"
FT /id="PRO_0000317639"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 77..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 57
FT /note="R -> G (in Ref. 1; BAB29342)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 109 AA; 13009 MW; F4AF85E025C63BAA CRC64;
MLGLLGNTTL VCWITGTALA FLMLLWLMAL CLFHRSQEHD VERNRVRQAR PRLFHGRRLR
LPRLVHHHHH HHVTGVTSVG VHHHHHHSPH RLHHHKHHHR HHHAHGARR
