ID   HRCU_RALSO              Reviewed;         357 AA.
AC   P35652;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 130.
DE   RecName: Full=Hypersensitivity response secretion protein HrcU;
GN   Name=hrcU; Synonyms=hrpN; OrderedLocusNames=RSp0864; ORFNames=RS01635;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OG   Plasmid megaplasmid Rsp.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=8316211; DOI=10.1007/bf00276936;
RA   Gough C.L., Genin S., Lopes V., Boucher C.A.;
RT   "Homology between the HrpO protein of Pseudomonas solanacearum and
RT   bacterial proteins implicated in a signal peptide-independent secretion
RT   mechanism.";
RL   Mol. Gen. Genet. 239:378-392(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- FUNCTION: Involved in the secretion of PopA, a proteinaceous elicitor
CC       of the hypersensitivity response in plants.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC       {ECO:0000305}.
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DR   EMBL; AJ245811; CAB58251.1; -; Genomic_DNA.
DR   EMBL; AL646053; CAD18015.1; -; Genomic_DNA.
DR   PIR; S35250; S35250.
DR   RefSeq; WP_011004161.1; NC_003296.1.
DR   AlphaFoldDB; P35652; -.
DR   SMR; P35652; -.
DR   STRING; 267608.RSp0864; -.
DR   MEROPS; N06.004; -.
DR   EnsemblBacteria; CAD18015; CAD18015; RSp0864.
DR   GeneID; 60503772; -.
DR   KEGG; rso:RSp0864; -.
DR   PATRIC; fig|267608.8.peg.4334; -.
DR   eggNOG; COG1377; Bacteria.
DR   HOGENOM; CLU_041013_1_3_4; -.
DR   OMA; VALKWDR; -.
DR   Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.40.1690.10; -; 1.
DR   InterPro; IPR006307; BsaZ.
DR   InterPro; IPR006135; T3SS_substrate_exporter.
DR   InterPro; IPR029025; T3SS_substrate_exporter_C.
DR   PANTHER; PTHR30531; PTHR30531; 1.
DR   Pfam; PF01312; Bac_export_2; 1.
DR   PRINTS; PR00950; TYPE3IMSPROT.
DR   SUPFAM; SSF160544; SSF160544; 1.
DR   TIGRFAMs; TIGR01404; FlhB_rel_III; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Hypersensitive response elicitation; Membrane; Plasmid;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..357
FT                   /note="Hypersensitivity response secretion protein HrcU"
FT                   /id="PRO_0000180959"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   357 AA;  38607 MW;  C99DEEE4A36EEE78 CRC64;
     MSDEKTEQPT DKKLEDAHRD GETAKSADLT AAAVLLSGCL LLALTASVFG ERWRALLDLA
     LDVDSSRHPL MTLKQTISHF ALQLVLMTLP VGFVFALVAW IATWAQTGVV LSFKPVELKM
     SAINPASGLK RIFSVRSMID LVKMIIKGVA VAAAVWKLIL ILMPSIVGAA YQSVMDIAEI
     GMTLLVRLLA AGGGLFLILG AADFGIQRWL FIRDHRMSKD EVKREHKNSE GDPHIKGERK
     KLARELADEA KPKQSVAGAQ AVVVNPTHYA VAIRYAPEEY GLPRIIAKGV DDEALALREE
     AAALGIPIVG NPPLARSLYR VDLYGPVPEP LFETVAEVLA WVGEMGASGT PGAEPQH