AP22_ORYSJ
ID AP22_ORYSJ Reviewed; 434 AA.
AC Q84TB5; Q10BG6;
DT 16-JAN-2019, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=APETALA2-like protein 2 {ECO:0000303|PubMed:28066457, ECO:0000303|Ref.1};
DE AltName: Full=Protein INDETERMINATE SPIKELET 1 {ECO:0000303|PubMed:22003982};
DE Short=OsIDS1 {ECO:0000303|PubMed:22003982};
GN Name=AP2-2 {ECO:0000303|PubMed:28066457};
GN Synonyms=AP2D2 {ECO:0000303|Ref.1}, IDS1 {ECO:0000303|PubMed:22003982};
GN OrderedLocusNames=LOC_Os03g60430 {ECO:0000305}, Os03g0818800 {ECO:0000305};
GN ORFNames=OJ1754_E06.6 {ECO:0000312|EMBL:AAO65862.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Dongjin;
RA Lee J., Lee D.Y., An G.;
RT "The AP2 subfamily genes in rice.";
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP TISSUE SPECIFICITY, AND REPRESSION BY MIR172.
RX PubMed=20017947; DOI=10.1186/1471-2229-9-149;
RA Zhu Q.-H., Upadhyaya N.M., Gubler F., Helliwell C.A.;
RT "Over-expression of miR172 causes loss of spikelet determinacy and floral
RT organ abnormalities in rice (Oryza sativa).";
RL BMC Plant Biol. 9:149-149(2009).
RN [6]
RP FUNCTION, DISRUPTION PHENOTYPE, REPRESSION BY MIR172, TISSUE SPECIFICITY,
RP AND DEVELOPMENTAL STAGE.
RX PubMed=22003982; DOI=10.1111/j.1365-313x.2011.04804.x;
RA Lee D.Y., An G.;
RT "Two AP2 family genes, SUPERNUMERARY BRACT (SNB) and OsINDETERMINATE
RT SPIKELET 1 (OsIDS1), synergistically control inflorescence architecture and
RT floral meristem establishment in rice.";
RL Plant J. 69:445-461(2012).
RN [7]
RP FUNCTION, REPRESSION BY MIR172, AND INTERACTION WITH TPR2/ASP1.
RX PubMed=26631749; DOI=10.1073/pnas.1521949112;
RA Wang L., Sun S., Jin J., Fu D., Yang X., Weng X., Xu C., Li X., Xiao J.,
RA Zhang Q.;
RT "Coordinated regulation of vegetative and reproductive branching in rice.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:15504-15509(2015).
RN [8]
RP FUNCTION, REPRESSION BY MIR172, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Zhonghua 11;
RX PubMed=28066457; DOI=10.3389/fpls.2016.01891;
RA Dai Z., Wang J., Zhu M., Miao X., Shi Z.;
RT "OsMADS1 represses microRNA172 in elongation of palea/lemma development in
RT rice.";
RL Front. Plant Sci. 7:1891-1891(2016).
CC -!- FUNCTION: Probable transcription factor (By similarity). Involved in
CC spikelet transition (Probable). Together with SNB, controls
CC synergistically inflorescence architecture and floral meristem
CC establishment via the regulation of spatio-temporal expression of
CC B- and E-function floral organ identity genes in the lodicules and of
CC spikelet meristem genes (PubMed:22003982). Prevents lemma and palea
CC elongation as well as grain growth (PubMed:28066457).
CC {ECO:0000250|UniProtKB:P47927, ECO:0000269|PubMed:22003982,
CC ECO:0000269|PubMed:28066457, ECO:0000305|PubMed:26631749}.
CC -!- SUBUNIT: May form homodimer (By similarity). Interacts with TPR2/ASP1
CC (PubMed:26631749). {ECO:0000250|UniProtKB:P47927,
CC ECO:0000269|PubMed:26631749}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366}.
CC -!- TISSUE SPECIFICITY: Highly expressed in developing panicles and in
CC young seedlings (PubMed:20017947, PubMed:22003982). Present at low
CC levels at all developmental stages (PubMed:22003982).
CC {ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982}.
CC -!- DEVELOPMENTAL STAGE: Detected in developing branch and spikelet
CC meristems at very early stages of inflorescence formation, and is
CC maintained uniformly in the spikelet meristems until floral organs
CC initiation. Present in some floral organ primordia.
CC {ECO:0000269|PubMed:22003982}.
CC -!- INDUCTION: Target of miR172 microRNA mediated cleavage, particularly
CC during floral organ development. {ECO:0000269|PubMed:22003982,
CC ECO:0000305|PubMed:20017947, ECO:0000305|PubMed:26631749,
CC ECO:0000305|PubMed:28066457}.
CC -!- DISRUPTION PHENOTYPE: Delayed transition from spikelet meristems to
CC floral meristems and altered floral architecture. The snb osids1 double
CC mutant, lacking both SNB and IDS1, exhibits a decreased number of
CC branches and spikelets within a panicle, as well as a strongly delayed
CC transition to a floral meristem, associated with abnormal spatio-
CC temporal expression of B- and E-function floral organ identity genes in
CC the lodicules and of spikelet meristem genes.
CC {ECO:0000269|PubMed:22003982}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. AP2
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABF99568.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY685113; AAW78367.1; -; mRNA.
DR EMBL; AC104433; AAO65862.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF99568.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008209; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015628369.1; XM_015772883.1.
DR AlphaFoldDB; Q84TB5; -.
DR SMR; Q84TB5; -.
DR STRING; 4530.OS03T0818800-00; -.
DR EnsemblPlants; Os03t0818800-01; Os03t0818800-01; Os03g0818800.
DR GeneID; 4334582; -.
DR Gramene; Os03t0818800-01; Os03t0818800-01; Os03g0818800.
DR KEGG; osa:4334582; -.
DR HOGENOM; CLU_035462_0_0_1; -.
DR InParanoid; Q84TB5; -.
DR OrthoDB; 1127651at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR ExpressionAtlas; Q84TB5; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009909; P:regulation of flower development; IMP:UniProtKB.
DR GO; GO:0080050; P:regulation of seed development; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR GO; GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:UniProtKB.
DR CDD; cd00018; AP2; 2.
DR Gene3D; 3.30.730.10; -; 2.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 2.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 2.
DR SUPFAM; SSF54171; SSF54171; 2.
DR PROSITE; PS51032; AP2_ERF; 2.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Repeat; Transcription; Transcription regulation.
FT CHAIN 1..434
FT /note="APETALA2-like protein 2"
FT /id="PRO_0000445989"
FT DNA_BIND 118..174
FT /note="AP2/ERF 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT DNA_BIND 210..267
FT /note="AP2/ERF 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 106..115
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT MOTIF 291..295
FT /note="EAR"
FT /evidence="ECO:0000250|UniProtKB:P47927"
FT COMPBIAS 9..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..87
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 434 AA; 47277 MW; D094987EFAFEAE10 CRC64;
MLLDLNVESP ERSGTSSSSV LNSGDAGGGG GGGGGGGLFR FDLLASSPDD DECSGEQHQL
PAASGIVTRQ LLPPPPPAAP SPAPAWQPPR RAAEDAALAQ RPVVAKKTRR GPRSRSSQYR
GVTFYRRTGR WESHIWDCGK QVYLGGFDTA HAAARAYDRA AIKFRGLEAD INFNLSDYED
DLKQMRNWTK EEFVHILRRQ STGFARGSSK FRGVTLHKCG RWEARMGQLL GKKYIYLGLF
DTEVEAARAY DRAAIRFNGR EAVTNFEPAS YNVDALPDAG NEAIVDGDLD LDLRISQPNA
RDSKSDVATT GLQLTCDSPE SSNITVHQPM GSSPQWTVHH QSTPLPPQHQ RLYPSHCLGF
LPNLQERPMD RRPELGPMPF PTQAWQMQAP SHLPLLHAAA SSGFSAGAGA GVAAATRRQP
PFPADHPFYF PPTA
