ID   HRCV_RALSO              Reviewed;         690 AA.
AC   P35656;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=Hypersensitivity response secretion protein HrcV;
GN   Name=hrcV; Synonyms=hrpO; OrderedLocusNames=RSp0863; ORFNames=RS01634;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OG   Plasmid megaplasmid Rsp.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=8316211; DOI=10.1007/bf00276936;
RA   Gough C.L., Genin S., Lopes V., Boucher C.A.;
RT   "Homology between the HrpO protein of Pseudomonas solanacearum and
RT   bacterial proteins implicated in a signal peptide-independent secretion
RT   mechanism.";
RL   Mol. Gen. Genet. 239:378-392(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- FUNCTION: Involved in the secretion of PopA, a proteinaceous elicitor
CC       of the hypersensitivity response in plants.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC       pore) family. {ECO:0000305}.
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DR   EMBL; AJ245811; CAB58250.1; -; Genomic_DNA.
DR   EMBL; M99633; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL646053; CAD18014.1; -; Genomic_DNA.
DR   PIR; S35251; S35251.
DR   RefSeq; WP_011004160.1; NC_003296.1.
DR   AlphaFoldDB; P35656; -.
DR   SMR; P35656; -.
DR   STRING; 267608.RSp0863; -.
DR   EnsemblBacteria; CAD18014; CAD18014; RSp0863.
DR   GeneID; 60503771; -.
DR   KEGG; rso:RSp0863; -.
DR   eggNOG; COG4789; Bacteria.
DR   HOGENOM; CLU_015346_3_0_4; -.
DR   OMA; PQFIGLQ; -.
DR   Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 1.10.8.540; -; 1.
DR   Gene3D; 3.40.30.60; -; 1.
DR   Gene3D; 3.40.50.12790; -; 1.
DR   InterPro; IPR042194; FHIPEP_1.
DR   InterPro; IPR042193; FHIPEP_3.
DR   InterPro; IPR042196; FHIPEP_4.
DR   InterPro; IPR025505; FHIPEP_CS.
DR   InterPro; IPR001712; T3SS_FHIPEP.
DR   InterPro; IPR006302; T3SS_HrcV.
DR   PANTHER; PTHR30161; PTHR30161; 1.
DR   Pfam; PF00771; FHIPEP; 1.
DR   PIRSF; PIRSF005419; FlhA; 1.
DR   PRINTS; PR00949; TYPE3IMAPROT.
DR   TIGRFAMs; TIGR01399; hrcV; 1.
DR   PROSITE; PS00994; FHIPEP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Hypersensitive response elicitation;
KW   Membrane; Plasmid; Protein transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..690
FT                   /note="Hypersensitivity response secretion protein HrcV"
FT                   /id="PRO_0000190026"
FT   TRANSMEM        14..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        229..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   690 AA;  73991 MW;  DA6FA8F32417E4D2 CRC64;
     MAKKNAIQDF SGEIGIAALV VAVVALMVLP LPTMLIDALL GLNITLSVVL LMVTMYIPSA
     TSLSAFPSLL LFTTLLRLSL NIASTKSILL HADAGHIIES FGKLVVGGNL VVGLVVFLII
     TTVQFIVIAK GSERVAEVGA RFTLDAMPGK QMSIDADLRA GHLSPEEARK RRALLAMESQ
     LHGGMDGAMK FVKGDAIAGL VITLVNILAG IVIGITYHNM TAGEAANRFA VLSIGDAMVS
     QIPSLLISVA AGVMITRVSD EEQAHKQSSL GMEIVRQLST SARAMFTASA LLMGFALVPG
     FPSFLFVALA TLIFVFGYTL RNRAKEGDGD EGDALPALLR EGSKGKAPTI AEQAPSFTVP
     VGVRLGAELA KGLDVPALDT AFQQGRHALA EALGLPFPGI AIWKADALQP DSYEVRVHDI
     PGEPVAVPDG HLLIPDLPEA LRAQAVEAAG LPNHPAPHWI APAHVAQDAA LSATGQRVER
     VIADHVVHVL RRSAHLFVGL QETQWMLERV TTDYPGLVAE AQKAVPAQRI ADVLRRLLEE
     QVPIRNMRAI LESLVVWGPK EKDTLMLVEY VRGDLGRQIA HQATGGTRQM PAILLDLSVE
     QTVRQAIKPT PAGNFLTLDP QQVEAIIMRL RGIMQGNPVE TPSALAIVTS MDIRRYVRRM
     IEPHLQALNV YSFQELGGYV DLRPVGKLVL