HRCV_RALSO
ID HRCV_RALSO Reviewed; 690 AA.
AC P35656;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=Hypersensitivity response secretion protein HrcV;
GN Name=hrcV; Synonyms=hrpO; OrderedLocusNames=RSp0863; ORFNames=RS01634;
OS Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OG Plasmid megaplasmid Rsp.
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=267608;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=8316211; DOI=10.1007/bf00276936;
RA Gough C.L., Genin S., Lopes V., Boucher C.A.;
RT "Homology between the HrpO protein of Pseudomonas solanacearum and
RT bacterial proteins implicated in a signal peptide-independent secretion
RT mechanism.";
RL Mol. Gen. Genet. 239:378-392(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=11823852; DOI=10.1038/415497a;
RA Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL Nature 415:497-502(2002).
CC -!- FUNCTION: Involved in the secretion of PopA, a proteinaceous elicitor
CC of the hypersensitivity response in plants.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000305}.
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DR EMBL; AJ245811; CAB58250.1; -; Genomic_DNA.
DR EMBL; M99633; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL646053; CAD18014.1; -; Genomic_DNA.
DR PIR; S35251; S35251.
DR RefSeq; WP_011004160.1; NC_003296.1.
DR AlphaFoldDB; P35656; -.
DR SMR; P35656; -.
DR STRING; 267608.RSp0863; -.
DR EnsemblBacteria; CAD18014; CAD18014; RSp0863.
DR GeneID; 60503771; -.
DR KEGG; rso:RSp0863; -.
DR eggNOG; COG4789; Bacteria.
DR HOGENOM; CLU_015346_3_0_4; -.
DR OMA; PQFIGLQ; -.
DR Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 1.10.8.540; -; 1.
DR Gene3D; 3.40.30.60; -; 1.
DR Gene3D; 3.40.50.12790; -; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR InterPro; IPR006302; T3SS_HrcV.
DR PANTHER; PTHR30161; PTHR30161; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR TIGRFAMs; TIGR01399; hrcV; 1.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Hypersensitive response elicitation;
KW Membrane; Plasmid; Protein transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..690
FT /note="Hypersensitivity response secretion protein HrcV"
FT /id="PRO_0000190026"
FT TRANSMEM 14..36
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 48..72
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..128
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 229..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 291..315
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 690 AA; 73991 MW; DA6FA8F32417E4D2 CRC64;
MAKKNAIQDF SGEIGIAALV VAVVALMVLP LPTMLIDALL GLNITLSVVL LMVTMYIPSA
TSLSAFPSLL LFTTLLRLSL NIASTKSILL HADAGHIIES FGKLVVGGNL VVGLVVFLII
TTVQFIVIAK GSERVAEVGA RFTLDAMPGK QMSIDADLRA GHLSPEEARK RRALLAMESQ
LHGGMDGAMK FVKGDAIAGL VITLVNILAG IVIGITYHNM TAGEAANRFA VLSIGDAMVS
QIPSLLISVA AGVMITRVSD EEQAHKQSSL GMEIVRQLST SARAMFTASA LLMGFALVPG
FPSFLFVALA TLIFVFGYTL RNRAKEGDGD EGDALPALLR EGSKGKAPTI AEQAPSFTVP
VGVRLGAELA KGLDVPALDT AFQQGRHALA EALGLPFPGI AIWKADALQP DSYEVRVHDI
PGEPVAVPDG HLLIPDLPEA LRAQAVEAAG LPNHPAPHWI APAHVAQDAA LSATGQRVER
VIADHVVHVL RRSAHLFVGL QETQWMLERV TTDYPGLVAE AQKAVPAQRI ADVLRRLLEE
QVPIRNMRAI LESLVVWGPK EKDTLMLVEY VRGDLGRQIA HQATGGTRQM PAILLDLSVE
QTVRQAIKPT PAGNFLTLDP QQVEAIIMRL RGIMQGNPVE TPSALAIVTS MDIRRYVRRM
IEPHLQALNV YSFQELGGYV DLRPVGKLVL