AP23_ORYSJ
ID AP23_ORYSJ Reviewed; 436 AA.
AC Q8H443; A0A0P0X4I8; B9FWB1;
DT 16-JAN-2019, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 133.
DE RecName: Full=APETALA2-like protein 3 {ECO:0000303|PubMed:28066457};
DE AltName: Full=Protein SUPERNUMERARY BRACT {ECO:0000303|PubMed:17144896};
GN Name=AP2-3 {ECO:0000303|PubMed:28066457};
GN Synonyms=SNB {ECO:0000303|PubMed:17144896};
GN OrderedLocusNames=LOC_Os07g13170 {ECO:0000305},
GN Os07g0235800 {ECO:0000312|EMBL:BAF21158.1};
GN ORFNames=OsJ_23635 {ECO:0000312|EMBL:EEE66848.1},
GN OSNPB_070235800 {ECO:0000312|EMBL:BAT00742.1},
GN P0407H12.124 {ECO:0000312|EMBL:BAC21448.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR
RP LOCATION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Dongjin; TISSUE=Flower;
RX PubMed=17144896; DOI=10.1111/j.1365-313x.2006.02941.x;
RA Lee D.-Y., Lee J., Moon S., Park S.Y., An G.;
RT "The rice heterochronic gene SUPERNUMERARY BRACT regulates the transition
RT from spikelet meristem to floral meristem.";
RL Plant J. 49:64-78(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP TISSUE SPECIFICITY, AND REPRESSION BY MIR172.
RX PubMed=20017947; DOI=10.1186/1471-2229-9-149;
RA Zhu Q.-H., Upadhyaya N.M., Gubler F., Helliwell C.A.;
RT "Over-expression of miR172 causes loss of spikelet determinacy and floral
RT organ abnormalities in rice (Oryza sativa).";
RL BMC Plant Biol. 9:149-149(2009).
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, REPRESSION BY MIR172, TISSUE SPECIFICITY,
RP AND DEVELOPMENTAL STAGE.
RX PubMed=22003982; DOI=10.1111/j.1365-313x.2011.04804.x;
RA Lee D.Y., An G.;
RT "Two AP2 family genes, SUPERNUMERARY BRACT (SNB) and OsINDETERMINATE
RT SPIKELET 1 (OsIDS1), synergistically control inflorescence architecture and
RT floral meristem establishment in rice.";
RL Plant J. 69:445-461(2012).
RN [8]
RP FUNCTION, REPRESSION BY MIR172, AND INTERACTION WITH TPR2/ASP1.
RX PubMed=26631749; DOI=10.1073/pnas.1521949112;
RA Wang L., Sun S., Jin J., Fu D., Yang X., Weng X., Xu C., Li X., Xiao J.,
RA Zhang Q.;
RT "Coordinated regulation of vegetative and reproductive branching in rice.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:15504-15509(2015).
RN [9]
RP FUNCTION, REPRESSION BY MIR172, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Zhonghua 11;
RX PubMed=28066457; DOI=10.3389/fpls.2016.01891;
RA Dai Z., Wang J., Zhu M., Miao X., Shi Z.;
RT "OsMADS1 represses microRNA172 in elongation of palea/lemma development in
RT rice.";
RL Front. Plant Sci. 7:1891-1891(2016).
CC -!- FUNCTION: Probable transcription factor (By similarity). Involved in
CC spikelet transition (Probable). Together with IDS1, controls
CC synergistically inflorescence architecture and floral meristem
CC establishment via the regulation of spatio-temporal expression of
CC B- and E-function floral organ identity genes in the lodicules and of
CC spikelet meristem genes (PubMed:22003982). Prevents lemma and palea
CC elongation as well as grain growth (PubMed:28066457). Regulates the
CC transition from spikelet meristem to floral meristem, spikelet meristem
CC determinancy and the floral organ development (PubMed:17144896).
CC {ECO:0000250|UniProtKB:P47927, ECO:0000269|PubMed:17144896,
CC ECO:0000269|PubMed:22003982, ECO:0000269|PubMed:28066457,
CC ECO:0000305|PubMed:26631749}.
CC -!- SUBUNIT: May form homodimer (By similarity). Interacts with TPR2/ASP1
CC (PubMed:26631749). {ECO:0000250|UniProtKB:P47927,
CC ECO:0000269|PubMed:26631749}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366,
CC ECO:0000269|PubMed:17144896}.
CC -!- TISSUE SPECIFICITY: Highly expressed in seedlings and developing
CC panicles (PubMed:17144896, PubMed:20017947, PubMed:22003982). Mostly
CC expressed in newly emerging spikelet meristems and, at low levels, in
CC shoots, roots, panicles, mature spikelets and sheaths
CC (PubMed:17144896). {ECO:0000269|PubMed:17144896,
CC ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982}.
CC -!- DEVELOPMENTAL STAGE: First detected in the boundary region of the shoot
CC apical meristem (SAM) and the surrounding sheath. Expressed at low
CC levels in vegetative organs, mostly in the sheaths. In inflorescence
CC tissues, observed in the branch meristem and spikelet meristem regions,
CC as well as in their vasculature and surrounding sheath
CC (PubMed:17144896). Accumulates in incipient rudimentary- and empty-
CC glume primordia (PubMed:22003982). Highly abundant in young developing
CC panicles, but becomes later present at low levels in developing
CC panicles and seeds. Found primarily in the boundary region of glume
CC primordia (PubMed:17144896). {ECO:0000269|PubMed:17144896,
CC ECO:0000269|PubMed:22003982}.
CC -!- INDUCTION: Target of miR172 microRNA mediated cleavage, particularly
CC during floral organ development. {ECO:0000269|PubMed:20017947,
CC ECO:0000269|PubMed:22003982, ECO:0000305|PubMed:26631749,
CC ECO:0000305|PubMed:28066457}.
CC -!- DISRUPTION PHENOTYPE: Delayed transition from spikelet meristems to
CC floral meristems, resulting in the production of multiple rudimentary
CC glumes in an alternative phyllotaxy. Abnormal development of additional
CC bracts leading to altered floral architecture, inculding lemma/palea-
CC like organs in place of empty glumes and lodicules, altered number of
CC stamens and carpels, and ectopic florets occurring in the axil of the
CC rachilla (PubMed:17144896, PubMed:22003982). The snb osids1 double
CC mutant, lacking both SNB and IDS1, exhibits a decreased number of
CC branches and spikelets within a panicle, as well as a strongly delayed
CC transition to a floral meristem, associated with abnormal spatio-
CC temporal expression of B- and E-function floral organ identity genes in
CC the lodicules and of spikelet meristem genes (PubMed:22003982).
CC {ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:22003982}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. AP2
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAT00742.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; DQ374663; ABD24033.1; -; mRNA.
DR EMBL; AP004303; BAC21448.1; -; Genomic_DNA.
DR EMBL; AP008213; BAF21158.1; -; Genomic_DNA.
DR EMBL; AP014963; BAT00742.1; ALT_INIT; Genomic_DNA.
DR EMBL; CM000144; EEE66848.1; -; Genomic_DNA.
DR RefSeq; XP_015647891.1; XM_015792405.1.
DR AlphaFoldDB; Q8H443; -.
DR SMR; Q8H443; -.
DR STRING; 4530.OS07T0235800-01; -.
DR EnsemblPlants; Os07t0235800-01; Os07t0235800-01; Os07g0235800.
DR GeneID; 4342787; -.
DR Gramene; Os07t0235800-01; Os07t0235800-01; Os07g0235800.
DR KEGG; osa:4342787; -.
DR eggNOG; ENOG502QSBE; Eukaryota.
DR HOGENOM; CLU_035462_0_0_1; -.
DR InParanoid; Q8H443; -.
DR OrthoDB; 1127651at2759; -.
DR PlantReactome; R-OSA-9608575; Reproductive meristem phase change.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000007752; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009909; P:regulation of flower development; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR GO; GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:UniProtKB.
DR CDD; cd00018; AP2; 2.
DR Gene3D; 3.30.730.10; -; 2.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 2.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 2.
DR SUPFAM; SSF54171; SSF54171; 2.
DR PROSITE; PS51032; AP2_ERF; 2.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..436
FT /note="APETALA2-like protein 3"
FT /id="PRO_0000445991"
FT DNA_BIND 122..178
FT /note="AP2/ERF 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT DNA_BIND 214..271
FT /note="AP2/ERF 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 110..119
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT MOTIF 295..299
FT /note="EAR"
FT /evidence="ECO:0000250|UniProtKB:P47927"
FT CONFLICT 134..138
FT /note="RWESH -> QWESQ (in Ref. 5; EEE66848)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 436 AA; 47439 MW; B22290C4A0E54872 CRC64;
MVLDLNVESP GGSAATSSSS TPPPPPDGGG GGYFRFDLLG GSPDEDGCSS PVMTRQLFPS
PSAVVALAGD GSSTPPLTMP MPAAAGEGPW PRRAADLGVA QSQRSPAGGK KSRRGPRSRS
SQYRGVTFYR RTGRWESHIW DCGKQVYLGG FDTAHAAARA YDRAAIKFRG LDADINFNLN
DYEDDLKQMR NWTKEEFVHI LRRQSTGFAR GSSKYRGVTL HKCGRWEARM GQLLGKKYIY
LGLFDSEIEA ARAYDRAAIR FNGREAVTNF DPSSYDGDVL PETDNEVVDG DIIDLNLRIS
QPNVHELKSD GTLTGFQLNC DSPEASSSVV TQPISPQWPV LPQGTSMSQH PHLYASPCPG
FFVNLREVPM EKRPELGPQS FPTSWSWQMQ GSPLPLLPTA ASSGFSTGTV ADAARSPSSR
PHPFPGHHQF YFPPTA
