ID   HRI1_KLULA              Reviewed;         241 AA.
AC   Q6CUE9;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Protein HRI1;
GN   Name=HRI1; OrderedLocusNames=KLLA0C05390g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HRI1 family. {ECO:0000305}.
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DR   EMBL; CR382123; CAH01291.1; -; Genomic_DNA.
DR   RefSeq; XP_452440.1; XM_452440.1.
DR   AlphaFoldDB; Q6CUE9; -.
DR   SMR; Q6CUE9; -.
DR   STRING; 28985.XP_452440.1; -.
DR   EnsemblFungi; CAH01291; CAH01291; KLLA0_C05390g.
DR   GeneID; 2892451; -.
DR   KEGG; kla:KLLA0_C05390g; -.
DR   eggNOG; ENOG502QTYD; Eukaryota.
DR   HOGENOM; CLU_097607_0_0_1; -.
DR   InParanoid; Q6CUE9; -.
DR   OMA; NVPNTHR; -.
DR   Proteomes; UP000000598; Chromosome C.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006612; P:protein targeting to membrane; IEA:EnsemblFungi.
DR   CDD; cd11692; HRI1_N_like; 1.
DR   Gene3D; 2.40.128.320; -; 1.
DR   InterPro; IPR031818; Hri1.
DR   InterPro; IPR038744; Hri1_N.
DR   InterPro; IPR043047; Hri1_N_sf.
DR   Pfam; PF16815; HRI1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..241
FT                   /note="Protein HRI1"
FT                   /id="PRO_0000410810"
SQ   SEQUENCE   241 AA;  27112 MW;  22F60FAAC68E80F6 CRC64;
     MVSLTKRVLF EVIPNPPDET TLTLSSTTNK GHYISVRPFV NAEGKEFPFE WAFGGTSDHI
     ELKKINERAN SLNFNFKFDT NVKLNVPETH RGVIKTVFKT WDSGLVEETG SVFPWGTEGT
     EVKFRELWQP VDPTRLEFVE LNNEKDVDQA ANSIALSVDN EEYEGLVIVV GRWIQGILFK
     KGVNTLDGIN LFRSQIDEKN SIVSLVKFGA DADKFPQEVL LNEGSITTSK GLEWSVIESN
     L