ID   HRP2_PLAFA              Reviewed;         241 AA.
AC   P05228;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Histidine-rich protein PFHRP-III;
DE   Flags: Precursor;
OS   Plasmodium falciparum.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5833;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   PubMed=3016741; DOI=10.1073/pnas.83.16.6065;
RA   Wellems T.E., Howard R.J.;
RT   "Homologous genes encode two distinct histidine-rich proteins in a cloned
RT   isolate of Plasmodium falciparum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 83:6065-6069(1986).
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DR   EMBL; K03509; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; M13987; AAA29617.1; -; Genomic_DNA.
DR   PIR; B25942; B25942.
DR   AlphaFoldDB; P05228; -.
DR   InterPro; IPR008779; Plasmodium_HRP.
DR   Pfam; PF05403; Plasmodium_HRP; 1.
PE   2: Evidence at transcript level;
KW   Malaria; Repeat; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..241
FT                   /note="Histidine-rich protein PFHRP-III"
FT                   /id="PRO_0000024541"
FT   REGION          52..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          195..241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        195..232
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   241 AA;  25719 MW;  0965FBA900DF0A7F CRC64;
     MVSFSKNKVL SAAVFASVLL LDNNNSEFNN NLFSKNAKGL NSNKRLLHES QAHAGDAHHA
     HHVADAHHAH HVADAHHAHH AANAHHAANA HHAANAHHAA NAHHAANAHH AANAHHAANA
     HHAANAHHAA NAHHAANAHH AANAHHAANA HHAANAHHAA DANHGFHFNL HDNNSHTLHH
     AKANACFDDS HHDDAHHDGA HHDDAHHDGA HHDDAHHDGA HHDGAHHDGA HHNATTHHLH
     H