ID   HRPA_ERWAM              Reviewed;          68 AA.
AC   Q46618;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 2.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Hrp pili protein HrpA;
DE   AltName: Full=TTSS pilin HrpA;
GN   Name=hrpA;
OS   Erwinia amylovora (Fire blight bacteria).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=552;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Ea321;
RA   Kim J.F., Wei Z.-M., Beer S.V.;
RT   "Complementation groups II and III of the Erwinia amylovora hrp gene
RT   cluster are required for secretion of harpin.";
RL   Phytopathology 85:1163-1163(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Ea321;
RX   PubMed=9045830; DOI=10.1128/jb.179.5.1690-1697.1997;
RA   Kim J.F., Wei Z.-M., Beer S.V.;
RT   "The hrpA and hrpC operons of Erwinia amylovora encode components of a type
RT   III pathway that secretes harpin.";
RL   J. Bacteriol. 179:1690-1697(1997).
RN   [3]
RP   FUNCTION.
RC   STRAIN=Ea110;
RX   PubMed=11401717; DOI=10.1046/j.1365-2958.2001.02455.x;
RA   Jin Q.-L., Hu W., Brown I., McGhee G., Hart P., Jones A.L., He S.Y.;
RT   "Visualization of secreted Hrp and Avr proteins along the Hrp pilus during
RT   type III secretion in Erwinia amylovora and Pseudomonas syringae.";
RL   Mol. Microbiol. 40:1129-1139(2001).
CC   -!- FUNCTION: Major structure protein of the hrp pilus, which is a
CC       component of the type III secretion system (TTSS, Hrp secretion system)
CC       required for effector protein delivery, parasitism, and pathogenicity.
CC       The hrp pilus functions as a conduit for protein delivery into the host
CC       cell. HrpA is required for the secretion of HrpN and DspA/E.
CC       {ECO:0000269|PubMed:11401717}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Fimbrium {ECO:0000250}.
CC       Note=Extracellular and secreted via type III secretion system.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HrpA type 2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB49172.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U56662; AAB49172.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_033477547.1; NZ_CP056034.1.
DR   AlphaFoldDB; Q46618; -.
DR   GeneID; 8913504; -.
DR   PATRIC; fig|665029.3.peg.561; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Fimbrium; Secreted; Virulence.
FT   CHAIN           1..68
FT                   /note="Hrp pili protein HrpA"
FT                   /id="PRO_0000226251"
FT   REGION          1..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   68 AA;  6914 MW;  77B73C1D8A950672 CRC64;
     MAGSSLTSAS TSASKTLESA MGQSLTESAN AQASKMKMDT QNSILDGKMD SASKSINSGH
     NAAKAIQF